924377-85-5
924377-85-5 structure
- Name: GSK 1702934A
- Chemical Name: GSK1702934A
- CAS Number: 924377-85-5
- Molecular Formula: C22H25N3O2S
- Molecular Weight: 395.52
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel TRP Channel
- Create Date: 2020-04-21 18:31:26
- Modify Date: 2025-08-28 18:51:42
-
GSK1702934A is a selective TRPC3 agonist. GSK1702934A modulates cardiac contractility and f arrhythmogenesis by activation of TRPC3[1][2].
| Name | GSK1702934A |
|---|
| Description | GSK1702934A is a selective TRPC3 agonist. GSK1702934A modulates cardiac contractility and f arrhythmogenesis by activation of TRPC3[1][2]. |
|---|---|
| Related Catalog | |
| Target |
TRPC3 |
| In Vitro | GSK1702934A is able to induce TRPC3/6-currents in HEK293 cells transduced with recombinant human TRPC3/6 with an EC50 of 0.08 mM and 0.44 mM, respectively[1]. GSK1702934A induces a transient, non-selective conductance and prolonged action potentials in TRPC3-overexpressing myocytes but not in wild-type myocytes[2]. GSK1702934A substantially promotes NCX currents in TRPC3-overexpressing myocytes[2]. |
| References |
| Molecular Formula | C22H25N3O2S |
|---|---|
| Molecular Weight | 395.52 |