Fluridone

Modify Date: 2025-08-24 17:28:58

Fluridone Structure
Fluridone structure
 Common Name Fluridone
CAS Number 59756-60-4 Molecular Weight 329.316
Density 1.3±0.1 g/cm3 Boiling Point 444.4±45.0 °C at 760 mmHg
Molecular Formula C19H14F3NO Melting Point 154-155°C
MSDS Chinese USA Flash Point 222.6±28.7 °C
Symbol GHS06 GHS09
GHS06, GHS09		 Signal Word Danger

 Use of Fluridone


Fluridone is an inhibitor of abscisic acid (ABA) biosynthesis. Fluridone suppresses the expression of AchnFAR and TF genes and reduces the formation of primary alcohols[1].

 Names

Name fluridone
Synonym More Synonyms

 Fluridone Biological Activity

Description Fluridone is an inhibitor of abscisic acid (ABA) biosynthesis. Fluridone suppresses the expression of AchnFAR and TF genes and reduces the formation of primary alcohols[1].
Related Catalog
References

[1]. Wei X, et al. MYB41, MYB107, and MYC2 promote ABA-mediated primary fatty alcohol accumulation via activation of AchnFAR in wound suberization in kiwifruit. Hortic Res. 2020;7(1):86.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 444.4±45.0 °C at 760 mmHg
Melting Point 154-155°C
Molecular Formula C19H14F3NO
Molecular Weight 329.316
Flash Point 222.6±28.7 °C
Exact Mass 329.102753
PSA 22.00000
LogP 3.70
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.568
Storage condition 0-6°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UU7786500
CHEMICAL NAME :
4(1H)-Pyridinone, 1-methyl-3-phenyl-5-(3-(trifluoromethyl)phenyl)-
CAS REGISTRY NUMBER :
59756-60-4
BEILSTEIN REFERENCE NO. :
1547990
LAST UPDATED :
199710
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C19-H14-F3-N-O
MOLECULAR WEIGHT :
329.34

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,418,1991
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2130 gm/m3/1H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A582,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,418,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,418,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
>250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,418,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,418,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,418,1991 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
34908 mg/kg/1Y-C
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0545242

 Safety Information

Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger
Hazard Statements H311-H411
Precautionary Statements P273-P280-P312
Personal Protective Equipment Eyeshields;Faceshields;Gloves
Hazard Codes N:Dangerousfortheenvironment;
Risk Phrases R51/53
Safety Phrases S60-S36/37
RIDADR UN 3077
RTECS UU7786500
Packaging Group III

 Synthetic Route

1-phenyl-3-(3-(trifluoromethyl)phenyl)acetone structure

1-phenyl-3-(3-(...

CAS#:59756-57-9

methylamine structure

methylamine

CAS#:74-89-5

~95%

Fluridone Structure

Fluridone

CAS#:59756-60-4

Literature: Eli Lilly and Company Patent: US4152136 A1, 1979 ;
1-phenyl-3-(3-(trifluoromethyl)phenyl)acetone structure

1-phenyl-3-(3-(...

CAS#:59756-57-9

methyl formate structure

methyl formate

CAS#:107-31-3

~%

Fluridone Structure

Fluridone

CAS#:59756-60-4

Literature: US4235619 A1, ;
1-phenyl-3-(3-(trifluoromethyl)phenyl)acetone structure

1-phenyl-3-(3-(...

CAS#:59756-57-9

Diethyl ether structure

Diethyl ether

CAS#:60-29-7

tert-Butoxy bis(dimethylamino)methane structure

tert-Butoxy bis...

CAS#:5815-08-7

methylamine structure

methylamine

CAS#:74-89-5

~%

Detail
Literature: US4152136 A1, ;

 Articles27

More Articles
Genotoxic and cytotoxic evaluation of the herbicide flurochloridone on Chinese hamster ovary (CHO-K1) cells.

Toxicol. In Vitro 26(1) , 157-63, (2012)

The in vitro effects of flurochloridone (FLC) and its formulations Twin Gold Pack® (25% a.i.) and Rainbow® (25% a.i.) were evaluated on Chinese hamster ovary (CHO-K1) cells by genotoxicity [sister chr...

Adsorption of diuron, fluridone and norflurazon on single-walled and multi-walled carbon nanotubes.

Sci. Total Environ. 439 , 1-7, (2012)

The sorption behaviors of diuron (DIU), fluridone (FLU) and norflurazon (NOR) by a single-walled carbon nanotube (SWCNT) and three multi-walled carbon nanotubes (MWCNT) samples including MWCNT10 (<10n...

Sorption of fluorinated herbicides to plant biomass-derived biochars as a function of molecular structure.

Bioresour. Technol. 102(21) , 9897-903, (2011)

Biochars produced at different heat treatment temperatures (HTT) are molecularly distinct and thus expected to show variable sorbent characteristics. We investigated the difference in sorption behavio...

 Synonyms

1-Methyl-3-phenyl-5-[3-(trifluoromethyl)phenyl]pyridin-4(1H)-one
1-Methyl-3-phenyl-5-[3-(trifluoromethyl)phenyl]-4(1H)-pyridinone
1-methyl-3-phenyl-5-(α,α,α-trifluoro-m-tolyl)-4-pyridone
Fluridone
Sonar
4(1H)-Pyridinone, 1-methyl-3-phenyl-5-[3-(trifluoromethyl)phenyl]-
Fluridon
Sonar X
1-methyl-3-phenyl-5-[3-(trifluoromethyl)phenyl]pyridin-4-one
1-Methyl-3-phenyl-5-(a,a,a-trifluoro-m-tolyl)-4-pyridone
MFCD00078682
Pride
EINECS 261-916-6
Brake
1-Methyl-3-phenyl-5-[3-(trifluormethyl)phenyl]pyridin-4(1H)-on
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