methyl formate

Modify Date: 2024-01-02 20:14:50

methyl formate Structure
methyl formate structure
Common Name methyl formate
CAS Number 107-31-3 Molecular Weight 60.052
Density 0.968 Boiling Point 31-33 ºC
Molecular Formula C2H4O2 Melting Point -100 °C
MSDS Chinese USA Flash Point -32 ºC
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

 Names

Name methyl formate
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.968
Boiling Point 31-33 ºC
Melting Point -100 °C
Molecular Formula C2H4O2
Molecular Weight 60.052
Flash Point -32 ºC
Exact Mass 60.021130
PSA 26.30000
LogP -0.23
Vapour density 2.1 (vs air)
Vapour Pressure 731.9±0.1 mmHg at 25°C
Index of Refraction 1.328
Stability Stable. Extremely flammable. Readily forms explosive mixtures with air. Note low flash point and very wide explosion limits. Incompatible with oxidizing agents.
Water Solubility 300 G/L (20 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LQ8925000
CHEMICAL NAME :
Formic acid, methyl ester
CAS REGISTRY NUMBER :
107-31-3
LAST UPDATED :
199712
DATA ITEMS CITED :
28
MOLECULAR FORMULA :
C2-H4-O2
MOLECULAR WEIGHT :
60.06
WISWESSER LINE NOTATION :
VHO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1622 mg/kg
REFERENCE :
IMSUAI Industrial Medicine and Surgery. (Northbrook, IL) V.18-42, 1949-73. For publisher information, see IOHSA5. Volume(issue)/page/year: 41,31,1972 *** REVIEWS *** ACGIH TLV-STEL 368 mg/m3 (150 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 246 mg/m3 (100 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 TOXICOLOGY REVIEW AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 20,517,1959 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 100 ppm (250 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,165,1971 OSHA PEL (Gen Indu):8H TWA 100 ppm (250 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 100 ppm (250 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 100 ppm (250 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 100 ppm (250 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 100 ppm (250 mg/m3);STEL 150 ppm (375 mg/m3) JAN 1993 OEL-AUSTRIA:TWA 100 ppm (250 mg/m3) JAN 1993 OEL-BELGIUM:TWA 100 ppm (246 mg/m3);STEL 150 ppm (369 mg/m3) JAN 1993 OEL-DENMARK:TWA 100 ppm (250 mg/m3) JAN 1993 OEL-FINLAND:TWA 100 ppm (250 mg/m3);STEL 150 ppm (375 mg/m3) JAN 1993 OEL-FRANCE:TWA 100 ppm (250 mg/m3) JAN 1993 OEL-GERMANY:TWA 100 ppm (250 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 100 ppm (250 mg/m3);STEL 200 ppm JAN 1993 OEL-THE PHILIPPINES:TWA 100 ppm (250 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 100 ppm (250 mg/m3);STEL 200 ppm (500 mg/m3) JAN 1993 OEL-TURKEY:TWA 100 ppm (250 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 100 ppm (250 mg/m3);STEL 150 ppm JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO METHYL FORMATE-air:10H TWA 100 ppm;STEL 150 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 33850 No. of Facilities: 80 (estimated) No. of Industries: 6 No. of Occupations: 22 No. of Employees: 7738 (estimated) No. of Female Employees: 1402 (estimated)

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger
Hazard Statements H224-H302 + H332-H319-H335
Precautionary Statements P210-P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)
Hazard Codes F+:Highlyflammable;Xn:Harmful;
Risk Phrases R12;R20/22;R36/37
Safety Phrases S9-S16-S24-S26-S33
RIDADR UN 1243 3/PG 1
WGK Germany 1
RTECS LQ8925000
Packaging Group I
Hazard Class 3
HS Code 2915130000

 Synthetic Route

 Customs

HS Code 2915120000
Summary 2915120000 salts of formic acid。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Articles39

More Articles
Urinary methanol and formic acid as indicators of occupational exposure to methyl formate.

Int. Arch. Occup. Environ. Health 73(6) , 410-4, (2000)

To evaluate the validity of methanol (MeOH) and formic acid (FA) in urine as biological indicators of methyl formate (MF) exposure in experimental and field situations.The subjects were 28 foundrymen ...

Identification of prostamides, fatty acyl ethanolamines, and their biosynthetic precursors in rabbit cornea.

J. Lipid Res. 56 , 1419-33, (2015)

Arachidonoyl ethanolamine (anandamide) and pros-taglandin ethanolamines (prostamides) are biologically active derivatives of arachidonic acid. Although available through different precursor phospholip...

A role for oleoylethanolamide in chronic lymphocytic leukemia.

Leukemia 28(7) , 1381-7, (2014)

Oleoylethanolamide (OEA) is a bioactive lipid that stimulates nuclear and G protein-coupled receptors and regulates appetite and fat metabolism. It has not previously been shown to have a role in canc...

 Synonyms

methyl-formate
Methyl methanoate
Formic acid methyl ester
Formic acid,methyl ester
Methyl formate
Caswell No. 570
EINECS 203-481-7
MFCD00003291
Methylformiaat [Dutch]
Formiate de methyle [French]
Methylformiat [German]
Mravencan methylnaty [Czech]
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