667880-11-7
667880-11-7 structure
- Name: ZINC00640089
- Chemical Name: ZINC00640089
- CAS Number: 667880-11-7
- Molecular Formula: C20H13F3N2O2
- Molecular Weight: 370.32
- Catalog: Research Areas Cancer
- Create Date: 2022-12-06 17:16:56
- Modify Date: 2024-04-02 21:22:05
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ZINC00640089 is a specific Lipocalin-2 (LCN2) inhibitor. ZINC00640089 inhibits cell proliferation, cell viability and reduces AKT phosphorylation levels in SUM149 cells. ZINC00640089 has good potential for research in inflammatory breast cancer (IBC)[1].
| Name | ZINC00640089 |
|---|
| Description | ZINC00640089 is a specific Lipocalin-2 (LCN2) inhibitor. ZINC00640089 inhibits cell proliferation, cell viability and reduces AKT phosphorylation levels in SUM149 cells. ZINC00640089 has good potential for research in inflammatory breast cancer (IBC)[1]. |
|---|---|
| Related Catalog | |
| Target |
LCN2[1]. |
| In Vitro | ZINC00640089 (0.01-100 µM; 72 h) reduces cell proliferation and cell viability in SUM149 cells[1]. ZINC00640089 (1, 10 µM; 15 min, 1 h) reduces the p-Akt levels in SUM149 cells[1]. Cell Viability Assay[1] Cell Line: SUM149 cells Concentration: 0.01-100 µM Incubation Time: 72 h Result: Reduced cell viability at concentrations of 1 µM or lower. Western Blot Analysis[1] Cell Line: SUM149 cells Concentration: 1, 10 µM Incubation Time: 15 min, 1 h, 24 h Result: Reduced the p-Akt protein levels 15 min and 1 h and changes in the p-Akt protein levels were not observed at 24 h. |
| Molecular Formula | C20H13F3N2O2 |
|---|---|
| Molecular Weight | 370.32 |