Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Torachrysone 8-O-glucoside

Torachrysone-8-O-b-D-glucoside could be isolated from root of Polygonum multiflorum. Torachrysone-8-O-b-D-glucoside increases the proliferation of DPCs (dermal papilla cells)[1].

  • CAS Number: 64032-49-1
  • MF: C20H24O9
  • MW: 408.399
  • Catalog: Metabolic Disease
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 676.9±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 239.8±25.0 °C

(S)-2-((S)-2-(tert-butoxycarbonylamino)-3-Methylbutanamido)propanoic acid

(tert-Butoxycarbonyl)-L-valyl-L-alanine is an alanine derivative[1].

  • CAS Number: 70396-18-8
  • MF: C13H24N2O5
  • MW: 288.34000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Prepro-von Willebrand factor (641-650) (bovine)

Prepro-von Willebrand factor (641-650) (bovine) is a fragment of Prepro-von Willebrand factor, which binds to type I collagen[1].

  • CAS Number: 143470-36-4
  • MF: C54H78N14O15S
  • MW: 1195.35
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TCRS-417

TCRS-417 (T417) is a small molecule compound capable of docking to the interface between PBX1 and its cognate DNA target sequence, effectively interfering with PBX1-DNA interaction. TCRS-417 can be used in the research of cancer, developmental disorders, inflammatory disorders, autoimmune diseases or neurodegenerative diseases[1].

  • CAS Number: 2032123-28-5
  • MF: C25H19FN2O5
  • MW: 446.43
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-Prenyljacareubin

7-Prenyljacareubin is a natural xanthone found in Garcinia gardneriana[1].

  • CAS Number: 94513-60-7
  • MF: C23H22O6
  • MW: 394.417
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 600.5±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 210.2±25.0 °C

2-((Tert-Butoxycarbonyl)(Methyl)Amino)-3-Methyl-3-Phenylbutanoic Acid

(Rac)-Taltobulin intermediate-1 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1].

  • CAS Number: 676487-35-7
  • MF: C17H25NO4
  • MW: 307.38
  • Catalog: Cancer
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 419.6±34.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 207.6±25.7 °C

HHQ

2-Heptyl-4-quinolone is an intermediate in the synthesis of the Pseudomonas quinolone signal (PQS) that controls swarming by positively regulating phenazine production. 2-Heptyl-4-quinolone induces the production of the phenazine-1-carboxylic acid (PCA)[1].

  • CAS Number: 40522-46-1
  • MF: C16H21NO
  • MW: 243.34400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-acetyl-alpha-endorphin

N-Acetyl-α-Endorphin is an acetylated α-Endorphin at N-terminal. α-Endorphin is an endogenous opioid peptide.

  • CAS Number: 88264-63-5
  • MF: C79H122N18O27S
  • MW: 1787.98
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-D-Orn(N3)-OH hydrochloride

H-D-Orn(N3)-OH hydrochloride is a click chemistry reagent containing an azide group.

  • CAS Number: 1858224-08-4
  • MF: C5H11ClN4O2
  • MW: 194.62
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2'-Fluorothymidine

2'-Fluorothymidine (2'-Fluoro-2'-deoxythymidine), a bioisostere of both thymidine (TdR) and methyluridine, is a putative highly selective substrate for thymidine kinase type 2 (TK2)[1].

  • CAS Number: 122799-38-6
  • MF: C10H13FN2O5
  • MW: 260.219
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

indium(iii) isopropoxide

Indium(III) Isopropoxide is an organo-metallic compound. Indium(III) Isopropoxide uesd as a hydrogen transfer catalyst for conversion of benzylic alcohols into aldehydes or ketones via Oppenauer oxidation. Indium(III) Isopropoxide also can be used as metal precursor[1][2].

  • CAS Number: 38218-24-5
  • MF: C3H8O.1/3In
  • MW: 292.07900
  • Catalog: Others
  • Density: 0.808 g/mL at 25ºC
  • Boiling Point: 82℃
  • Melting Point: 145ºC (dec.)
  • Flash Point: 10ºC

Isomucronulatol 7-O-beta-glucoside

Isomucronulatol 7-O-glucoside is a flavonoid isolated from the roots of A. membranaceus. Isomucronulatol 7-O-glucoside exhibits weak inhibitory effects on LPS-stimulated production IL-12 p40 in vitro and has potential anti-inflammatory effect[1].

  • CAS Number: 136087-29-1
  • MF: C23H28O10
  • MW: 464.462
  • Catalog: Inflammation/Immunology
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 641.5±55.0 °C at 760 mmHg
  • Melting Point: 81-82 °C
  • Flash Point: 341.8±31.5 °C

TAMRA alkyne, 6-isomer

TAMRA alkyne, 6-isomer is a linker of TAMRA which is a xanthene dye with orange emission that is commonly used for oligonucleotide labeling and amino acid sequencing. The addition of the alkyne groups allows for it to be reacted with an azide for copper-catalyzed Click Chemistry[1].

  • CAS Number: 1352649-44-5
  • MF: C28H25N3O4
  • MW: 467.52
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Dazdotuftide

Dazdotuftide is a active compound and can be used as a immunomodulator[1].

  • CAS Number: 2522933-44-2
  • MF: C43H68N13O13P
  • MW: 1006.05
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Quinolinium,1-ethyl-2-[(1-ethyl-4(1H)-quinolinylidene)methyl]-, iodide (1:1)

Ethyl red (1,1'-Diethyl-2,4'-cyanine) iodide is an azo dye and acid–base indicator[1][2].

  • CAS Number: 634-21-9
  • MF: C23H23IN2
  • MW: 454.34700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 158-160ºC(lit.)
  • Flash Point: N/A

lycoclavanol

Lycoclavanol is a serratane-type triterpenoid, which can be isolated from the dried whole plants of Lycopodium japonicum[1].

  • CAS Number: 13956-51-9
  • MF: C30H50O3
  • MW: 458.72
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 566.1±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 232.0±24.7 °C

25-Methoxyalisol A

25-O-Methylalisol A is a protostane triterpenoids isolated from Alisma orientale. The dried rhizomes of the aquatic plant Alisma orientale known as Rhizoma Alismatis is a common traditional Chinese medicine used for diuretic, anti-inflammatory, and hypolipidemic purposes, as well as the treatment of diabetes[1].

  • CAS Number: 155801-00-6
  • MF: C31H52O5
  • MW: 504.742
  • Catalog: Metabolic Disease
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 618.0±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 190.4±25.0 °C

Acyl-CoA oxidase

Acyl-CoA oxidase (ACO) catalyses the first and rate-determining step of the peroxisomal beta-oxidation of fatty acids and a major producer of hydrogen peroxide (H2O2)[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

glycyl-prolyl-glutamic acid

Gly-Pro-Glu is a neuroactive peptide with a potent action on acetylcholine release. Gly-Pro-Glu is the N-terminal tripeptide of insulin-like growth factor-I. Gly-Pro-Glu inhibits glutamate binds to N-methyl-D-aspartate (NMDA) receptor with an IC50 value of 14.7 μM. Gly-Pro-Glu can be used for the research of neuroprotection [1][2].

  • CAS Number: 32302-76-4
  • MF: C12H19N3O6
  • MW: 301.29600
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bis(2,5-dioxopyrrolidin-1-yl) octadecanedioate

Bis(2,5-dioxopyrrolidin-1-yl) octadecanedioate is a linking reagent used in organic synthesis[1].

  • CAS Number: 191091-33-5
  • MF: C26H40N2O8
  • MW: 508.60
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

mephenoxalone

Mephenoxalone inhibits neuron transmission and can relax skeletal muscles by inhibiting the reflex arc[1].

  • CAS Number: 70-07-5
  • MF: C11H13NO4
  • MW: 223.23
  • Catalog: Bcl-2 Family
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 440.0±18.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 219.9±21.2 °C

Trimethoprim 3-oxide

Trimethoprim 3-oxide is the urinary metabolite of trimethoprim.

  • CAS Number: 27653-67-4
  • MF: C14H18N4O4
  • MW: 306.31700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Toluidine Blue

Toluidine Blue is a basic thiazine metachromatic dye with high affinity for acidic tissue components. Toluidine Blue has wide applications in vital staining in living tissues and a special stain[1].

  • CAS Number: 92-31-9
  • MF: C15H16ClN3S
  • MW: 305.826
  • Catalog: Apoptosis
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-(4-Aminobenzoyl)-L-glutamic acid-d4

N-(4-Aminobenzoyl)-L-glutamic acid-d4 is the deuterium labeled 4-Nitrobenzoic acid[1].

  • CAS Number: 461426-34-6
  • MF: C12H10D4N2O5
  • MW: 270.27
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,2-Distearoyl-sn-glycero-3-phosphate-d70 sodium

1,2-Distearoyl-sn-glycero-3-phosphate-d70 (sodium) is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphate.

  • CAS Number: 327179-02-2
  • MF: C39H6D70NaO8P
  • MW: 797.41
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Calcium gluconate

Calcium gluconate is a mineral supplement, manufactured by the neutralization of gluconic acid with lime or calcium carbonate.

  • CAS Number: 299-28-5
  • MF: C6H12O7.1/2Ca
  • MW: 216.20
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 673.6ºC at 760 mmHg
  • Melting Point: 195°C
  • Flash Point: 375.2ºC

(S)-Tenofovir

(S)-Tenofovir ((S)-GS 1278) is the less active S-enantiomer of Tenofovir. Tenofovir is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV)[1].

  • CAS Number: 147127-19-3
  • MF: C9H14N5O4P
  • MW: 287.21200
  • Catalog: Infection
  • Density: 1.79g/cm3
  • Boiling Point: 616.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 326.4ºC

2,6-Dimethyltyrosine HCl

2,6-DiMethyltyrosine HCl is a tyrosine derivative[1].

  • CAS Number: 80110-73-2
  • MF: C11H16ClNO3
  • MW: 245.703
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Z-Lys(Z)-Osu

Z-Lys(Z)-OSu is a lysine derivative[1].

  • CAS Number: 21160-83-8
  • MF: C26H29N3O8
  • MW: 511.524
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

G-15

G15 is a high affinity and selective G-protein-coupled estrogen receptor (GPER) antagonist with a Ki of 20 nM[1][2].

  • CAS Number: 1161002-05-6
  • MF: C19H16BrNO2
  • MW: 370.24
  • Catalog: Cancer
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 462.7±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 233.7±28.7 °C