676487-35-7

676487-35-7 structure

Name: 2-((Tert-Butoxycarbonyl)(Methyl)Amino)-3-Methyl-3-Phenylbutanoic Acid
Chemical Name: Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-N,β,β-trimethyl-
CAS Number: 676487-35-7
Molecular Formula: C₁₇H₂₅NO₄
Molecular Weight: 307.38
Catalog: Research Areas Cancer
Create Date: 2021-11-16 12:43:32
Modify Date: 2025-11-05 15:10:41
(Rac)-Taltobulin intermediate-1 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1].

Name	Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-N,β,β-trimethyl-
Synonyms	MFCD24539079 N,β,β-Trimethyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}phenylalanine Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-N,β,β-trimethyl-

Description	(Rac)-Taltobulin intermediate-1 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Loganzo F, et al. HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Cancer Res. 2003 Apr 15;63(8):1838-45.