MEL24 is an Mdm2 E3 ligase inhibitor that reduces cell survival and increases sensitivity to DNA damaging agents in a p53-dependent manner for in vitro antitumor studies[1].
Protein Kinase C Peptide Substrate is targeted to a specific cellular compartment in a manner dependent on second messengers and on specific adapter proteins in response to extracellular signals that activate G-protein-coupled receptors, tyrosine kinase receptors, or tyrosine kinase-coupled receptors. Protein Kinase C Peptide Substrate then regulates various physiological functions including the activation of nervous, endocrine, exocrine, inflammatory, and immune systems[1].
NQTrp, an aromatic naphthoquinone-tryptophan hybrid molecule, an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects. NQTrp inhibits the in vitro aggregation of hexapeptide (41GCWMLY46 within the N-terminus of γD-crystallin) as well as full-length γD-crystallin[1].
Anemarrhenasaponin A2 (Schidigerasaponin F2;Timosaponin AII) is a steroidal saponin isolated from the rhizomes of Anemarrhena asphodeloides. Anemarrhenasaponin A2 inhibits ADP-induced platelet aggregation[1].
N,N-Diphenylacetamide (N-Acetyldiphenylamine) has N,N-disubstituted amide group and can be used as a mono- as well as a bidentate ligand generating four-membered chelate rings[1].
Ruzadolane is a non-narcotic, centrally-acting analgesic agent.
iNOs-IN-3 (Compound 2d) is an orally active nitric oxide synthase (iNOS) inhibitor (IC50=3.342 µM). iNOs-IN-3 shows anti-inflammatory activity and can be used in LPS-induced acute lung injury (ALI) research[1].
Fmoc-Lys(Biotin)-OH is a lysine derivative[1].
Cepharanoline is a compound isolated from Stephania cepharantha Hayata. Cepharanoline has proliferative activities[1].
3-DL-Cpa-OH is an alanine derivative[1].
Chlorempenthrin is a synthetic pyrethroid insecticide[1].
Cytochalasin K (Compounds 7) is a cytochalasin that inhibits wheat root elongation with an IC50 of 22.58 μM[1].
N-Acetyl-S-[3-acetamino-6-hydroxphenyl]-cysteine allyl ester-d5 is the deuterium labeled N-Acetyl-S-[3-acetamino-6-hydroxphenyl]-cysteine allyl ester[1].
MAT2A inhibitor 3 is a methionine adenosyltransferase 2A (MAT2A) inhibitor extracted from patent WO2020123395A1, compound 24, has an IC50 of <200 nM. MAT2A inhibitor 3 can be used for the research of cancers[1].
1,3,5-Tribromobenzene-d3 is the deuterium labeled 1,3,5-Tribromobenzene[1].
α-L-Rhamnose monohydrate is a component of the plant cell wall pectic polysaccharides rhamnogalacturonan I and rhamnogalacturonan II. α-L-Rhamnose monohydrate is also a component of bacterial polysaccharides where it plays an important role in pathogenicity.
Triphenylamine-d15 is the deuterium labeled Triphenylamine[1].
Antiproliferative agent-29 (Compound 16) is a triterpenoid isolated from the seeds of Peganum harmala L. Antiproliferative agent-29 has antiproliferative activity and has potential for cancer research[1].
Amyloid β-Protein (1-24) is a biologically active peptide.
Caulophyllumine A is a natural product that can be isolated from blue cohosh[1].
Efprezimod alfa is an active peptide. Efprezimod alfa can be used for various biochemical studies.
Rocaglaol induces apoptosis and cell cycle arrest in LNCaP cells[1].
Monochlorobimane is a fluorescent dye (λex=380 nm, λem=470 nm).
Cistanoside F is a phenylethanoid glycosid isolated from Cistanche deserticola, with antioxidative effect[1].
Dielaidoylphosphatidylethanolamine is a liposome used to deliver drugs[1].
Dap-NE hydrochloride (GMP) is Dap-NE hydrochloride (HY-78932A) produced by using GMP guidelines. Dap-NE hydrochloride is an intermediate used in the synthesis of antibody-drug conjugates (ADCs)[1].
Oleuroside is a phenolic secoiridoid in olive. Oleuroside can protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing[1].
Glycyl-l-serine is a serine derivative[1].