MEL24
Modify Date: 2025-08-22 07:23:09
MEL24 structure
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Common Name | MEL24 | ||
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| CAS Number | 642072-48-8 | Molecular Weight | 326.35 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H18N4O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MEL24MEL24 is an Mdm2 E3 ligase inhibitor that reduces cell survival and increases sensitivity to DNA damaging agents in a p53-dependent manner for in vitro antitumor studies[1]. |
| Name | MEL24 |
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| Description | MEL24 is an Mdm2 E3 ligase inhibitor that reduces cell survival and increases sensitivity to DNA damaging agents in a p53-dependent manner for in vitro antitumor studies[1]. |
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| Related Catalog | |
| In Vitro | MEL24 作用于 293T 细胞，ED50 值为 9.2 μM[1]。 MEL24（15 μM，6 小时）增加 Mdm2、p53 和 MdmX 的水平并激活 p53，抑制 HCT116 细胞（p53 野生型）中内源性 MdmX 的降解[1]。 |
| References |
| Molecular Formula | C17H18N4O3 |
|---|---|
| Molecular Weight | 326.35 |