Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

NCI 240899

True Blue (NCI 240899) is a fluorescent dye, as neuronal retrograde tracer (excitation wavelength 395-425 nm, barrier filter 450 nm). True Blue can label neuron and has no effects on neuronal survival[1][2].

  • CAS Number: 71431-30-6
  • MF: C20H18Cl2N4O2
  • MW: 417.28900
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: 600.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 317.1ºC

6-NBDG

6-NBDG is a fluorescent glucose analogue, it can be used for fluorescence imaging and monitoring glucose transport and uptake. 6-NBDG can be used as a fluorescent probe for detecting macrophage-rich atherosclerotic plaques[1][2].

  • CAS Number: 108708-22-1
  • MF: C12H14N4O8
  • MW: 342.262
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 729.5±70.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 395.0±35.7 °C

Biotinyl-Tyr-Val-Ala-Asp-chloromethylketone

Biotin-YVAD-CMK is a biological active peptide.

  • CAS Number: 402474-75-3
  • MF: C32H45ClN6O9S
  • MW: 725.25
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 1163.8±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 657.7±34.3 °C

Cymipristone

Cymipristone, a progesterone receptor antagonist, is used potentially for termination of intrauterine pregnancy.

  • CAS Number: 329971-40-6
  • MF: C34H43NO2
  • MW: 497.71
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,6,6-Trimethyl-2-cyclohexene-1,4-dione

Ketoisophorone (4-Oxoisophorone) is a key intermediate in the synthesis of carotenoids and flavouring agents. Ketoisophorone is an industrially important cyclic endione[1].

  • CAS Number: 1125-21-9
  • MF: C9H12O2
  • MW: 152.190
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 214.2±0.0 °C at 760 mmHg
  • Melting Point: 26-28 °C(lit.)
  • Flash Point: 96.1±0.0 °C

Captopril EP Impurity B

Captopril EP Impurity B is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM)[1][2][3].

  • CAS Number: 80629-35-2
  • MF: C9H14BrNO3
  • MW: 264.11600
  • Catalog: Others
  • Density: 1.555±0.06 g/cm3 (20 ºC 760 Torr)
  • Boiling Point: N/A
  • Melting Point: 110-114 ºC
  • Flash Point: N/A

D-3,4-Dichloro Phenylalanine

H-D-Phe(3,4-DiCl)-OH is D-3,4-Dichlorophenylalanine, a amino acid derivative. H-D-Phe(3,4-DiCl)-OH shows protein synthesis activity[1].

  • CAS Number: 52794-98-6
  • MF: C9H9Cl2NO2
  • MW: 234.079
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 370.6±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 177.9±27.9 °C

Boc-Thr-OH

Boc-Thr-OH is a threonine derivative[1].

  • CAS Number: 2592-18-9
  • MF: C9H17NO5
  • MW: 219.235
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 387.1±37.0 °C at 760 mmHg
  • Melting Point: 80-82 °C(lit.)
  • Flash Point: 187.9±26.5 °C

Chrysoeriol 7-apiosylglucoside

3'-Methoxyapiin (Graveobioside B) is a flavone. 3'-Methoxyapiin can be found in Uraria crinite and celery[1][2].

  • CAS Number: 33579-63-4
  • MF: C27H30O15
  • MW: 594.51800
  • Catalog: Others
  • Density: 1.72±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 214-216 ºC
  • Flash Point: N/A

RCM 1

RCM-1 is a FOXM1 inhibitor.

  • CAS Number: 339163-65-4
  • MF: C20H12N2OS4
  • MW: 424.58
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Methyl-2-oxo-2H-chromen-7-yl octanoate

4-Methylumbelliferyl octanoate is a octoate. 4-Methylumbelliferyl octanoate can be used as a s ubstrate of hog pancreatic lipase[1].

  • CAS Number: 20671-66-3
  • MF: C18H22O4
  • MW: 302.365
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 441.1±40.0 °C at 760 mmHg
  • Melting Point: 44ºC ± 1ºC
  • Flash Point: 219.7±25.7 °C

N'-Fmoc-L-lysine

H-Lys(Fmoc)-OH is a lysine derivative[1].

  • CAS Number: 84624-28-2
  • MF: C21H24N2O4
  • MW: 368.426
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 609.9±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 322.6±31.5 °C

Endotoxin Inhibitor

Endotoxin inhibitor a synthetic peptide that binds lipid A with high affinity, thereby detoxifying LPS (HY-D1056) and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor inhibits the febrile response to LPS with very low toxicity and lethality[1].

  • CAS Number: 147396-10-9
  • MF: C55H97N15O12S2
  • MW: 1224.58000
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-acetyl-D-talosamine-13C

L-Talose-13C-1 is the 13C labeled L-Talose[1].

  • CAS Number: 875654-29-8
  • MF: C713CH15NO6
  • MW: 222.20
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

pTH-Related Protein (1-37) (human, mouse, rat) trifluoroacetate salt

pTH-Related Protein (1-37) (human, mouse, rat), the peptide analogue of pTH-Related Protein (pTHrP). pTHrP refers to parathyroid-hormone-related protein, involved in physiological regulation of bone formation[1].

  • CAS Number: 206010-80-2
  • MF: C197H317N63O53
  • MW:
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Phosphinic acid, P-[1-(5-chlorobenzo[b]thien-3-yl)-2-[[(1E)-2-(3,4-difluorophenyl)ethenyl]amino]-2-oxoethyl]-P-methyl-

Chymase-IN-2 is a chymase modulator which is useful in the treatment of inflammatory and serine protease mediated disorders.

  • CAS Number: 936366-22-2
  • MF: C19H15ClF2NO3PS
  • MW: 441.82
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

D-Nonamannuronic acid

D-Nonamannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Nonamannuronic acid can be used for the research of pain and vascular dementia[1][2][3][4].

  • CAS Number: 862694-99-3
  • MF: C54H74O55
  • MW: 1603.13
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cassyfiline

Cassyfiline (Cassythine) is an aporphine alkaloid. Cassyfiline has potent vasorelaxing effects on precontracted rat aortic preparations with an IC50 of 0.09 μM[1].

  • CAS Number: 4030-51-7
  • MF: C19H19NO5
  • MW: 341.36
  • Catalog: Cardiovascular Disease
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 552.2±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 287.8±30.1 °C

Fmoc-HoCys(ACM)-OH

Fmoc-HoCys(ACM)-OH, a homolog of cysteine, is synthesized from L-methionine. Fmoc-HoCys(ACM)-OH also can be used for the synthesis of solid phase peptide[1].

  • CAS Number: 150281-21-3
  • MF: C22H24N2O5S
  • MW: 428.501
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 731.2±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 396.0±32.9 °C

Broussonol E

Broussonol E is a diprenylated flavonol. Broussonol E can be isolated from the leaves of Broussonetia kazinoki. Unlike some dinonylated flavonol derivatives, Broussonol E has no cytotoxicity to human tumor cell lines (A549, HCT-8, KB)[1].

  • CAS Number: 363134-28-5
  • MF: C25H26O7
  • MW: 438.470
  • Catalog: Cancer
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 687.5±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 235.1±25.0 °C

Norcaesalpinin E

Norcaesalpinin E is a natural cassane-type diterpene found in the seed kernels of Caesalpinia crista[1].

  • CAS Number: 854038-96-3
  • MF: C21H28O6
  • MW: 376.443
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 499.5±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 255.9±28.7 °C

1-allyl-4-methylbenzene

4-Allyltoluene, an aromatic compound, can elicite antennal olfactory response of Mediterranean fruit fly measured by electroantennography (EAG)[1].

  • CAS Number: 3333-13-9
  • MF: C10H12
  • MW: 132.20200
  • Catalog: Others
  • Density: 0.88 g/cm3
  • Boiling Point: 182.7ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 55.7ºC
  • CAS Number: 19254-30-9
  • MF: C21H20O12
  • MW: 464.37600
  • Catalog: Metabolic Disease
  • Density: 1.809g/cm3
  • Boiling Point: 833.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 293.9ºC

8-Bromo-AMP

8-Bromo-AMP (8-Bromoadenosine 5'-monophosphate) is a membrane permeable cAMP analogue. 8-Bromo-AMP can improve the ability of the heart to recover from ischemia and reperfusion by increasing the levels of ATP, ADP, and total adenine nucleotides[1][2].

  • CAS Number: 23567-96-6
  • MF: C10H11BrN5O7P
  • MW: 424.10100
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(13α)-11,15-Dihydroxykaur-16-en-18-oic acid

(4α,11β,15β)-11,15-Dihydroxykaur-16-en-19-oic acid is a compound isolated from the Tunisian Pulicaria laciniata (Coss.et Kral.) Thell. flowers[1].

  • CAS Number: 57719-76-3
  • MF: C20H30O4
  • MW: 334.45
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 512.6±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 277.9±26.6 °C

N-Acetyl-S-allyl-L-cysteine-d3

N-Acetyl-S-allyl-L-cysteine-d3 is the deuterium labeled Fluometuron[1].

  • CAS Number: 1331907-55-1
  • MF: C8H10D3NO3S
  • MW: 206.28
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 121-122°C
  • Flash Point: N/A

3-Methyl-L-phenylalanine

3-Amino-3-(m-tolyl)propanoic acid is a phenylalanine derivative[1].

  • CAS Number: 68208-17-3
  • MF: C10H13NO2
  • MW: 179.216
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 322.8±30.0 °C at 760 mmHg
  • Melting Point: 210-212ºC
  • Flash Point: 149.0±24.6 °C

Ac-Gly-BoroPro

Ac-Gly-BoroPro is a selective FAP inhibitor with a Ki of 23 nM.

  • CAS Number: 886992-99-0
  • MF: C8H15BN2O4
  • MW: 214.027
  • Catalog: Peptides
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

MnTE-2-PyP chloride

MnTE-2-PyP (BMX-010) chloride is a ROS scavenger and potent radioprotector. MnTE-2-PyP also is a manganese porphyrin, protects normal prostate tissue from radiation damage. MnTE-2-PyP can be used for the research of diabetic prostate cancer[1].

  • CAS Number: 219818-60-7
  • MF: C48H44Cl5MnN8
  • MW: 965.12
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

L-Phenylalanine hydrochloride

L-Phenylalanine hydrochloride is a phenylalanine derivative[1].

  • CAS Number: 17585-69-2
  • MF: C9H12ClNO2
  • MW: 201.65000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 307.5ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 139.8ºC