Endotoxin Inhibitor
Modify Date: 2025-08-25 18:37:57
Endotoxin Inhibitor structure
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Common Name | Endotoxin Inhibitor | ||
|---|---|---|---|---|
| CAS Number | 147396-10-9 | Molecular Weight | 1224.58000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C55H97N15O12S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Endotoxin InhibitorEndotoxin inhibitor a synthetic peptide that binds lipid A with high affinity, thereby detoxifying LPS (HY-D1056) and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor inhibits the febrile response to LPS with very low toxicity and lethality[1]. |
| Name | h-lys-thr-lys-cys-lys-phe-leu-lys-lys-cys-oh |
|---|---|
| Synonym | More Synonyms |
| Description | Endotoxin inhibitor a synthetic peptide that binds lipid A with high affinity, thereby detoxifying LPS (HY-D1056) and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor inhibits the febrile response to LPS with very low toxicity and lethality[1]. |
|---|---|
| Related Catalog | |
| In Vivo | Endotoxin inhibitor (i.p., 0.5 mg/kg) 可以显著减弱热暴露引起的 IL-1β、COX-2、IκB-β 和 LPS 活性的 mRNA 增加，以及在老年大鼠中热暴露引起的低体温和血浆 ACTH 和儿茶酚胺反应作用[1]。 |
| References |
| Molecular Formula | C55H97N15O12S2 |
|---|---|
| Molecular Weight | 1224.58000 |
| Exact Mass | 1223.69000 |
| PSA | 526.15000 |
| LogP | 4.81840 |
| k-t-k-c-k-f-l-k-k-c |
| lys-thr-lys-cys-lys-phe-leu-lys-lys-cys |
| endotoxin inhibitor |