2130878-25-8
2130878-25-8 structure
- Name: BCL6 inhibitor 8c
- Chemical Name: BCL6 inhibitor 8c
- CAS Number: 2130878-25-8
- Molecular Formula: C20H20ClN3O5
- Molecular Weight: 417.846
- Catalog: Research Areas Cancer
- Create Date: 2020-01-12 15:53:10
- Modify Date: 2023-01-11 17:16:31
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A novel potent, in vivo-active BCL6 inhibitor with IC50 of 0.1 uM in ELISA assays; exhibits good cellular BCL6BTB/ BCoR PPI inhibitory activity in the submicromolar range (M2H IC50=0.72 uM), showed a good pharmacokinetic profile, which is acceptable for both in vitro and in vivo studies.
| Name | BCL6 inhibitor 8c |
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| Description | A novel potent, in vivo-active BCL6 inhibitor with IC50 of 0.1 uM in ELISA assays; exhibits good cellular BCL6BTB/ BCoR PPI inhibitory activity in the submicromolar range (M2H IC50=0.72 uM), showed a good pharmacokinetic profile, which is acceptable for both in vitro and in vivo studies. |
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| References | References 1. Yasui T, et al. Bioorg Med Chem. 2017 Sep 1;25(17):4876-4886. View Related Products by Target Bcl-2 |
| Molecular Formula | C20H20ClN3O5 |
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| Molecular Weight | 417.846 |
| Hazard Codes | Xi |
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