NCI 240899

Modify Date: 2024-01-09 10:04:08

NCI 240899 Structure
NCI 240899 structure
Common Name NCI 240899
CAS Number 71431-30-6 Molecular Weight 417.28900
Density N/A Boiling Point 600.6ºC at 760 mmHg
Molecular Formula C20H18Cl2N4O2 Melting Point N/A
MSDS N/A Flash Point 317.1ºC

 Use of NCI 240899


True Blue (NCI 240899) is a fluorescent dye, as neuronal retrograde tracer (excitation wavelength 395-425 nm, barrier filter 450 nm). True Blue can label neuron and has no effects on neuronal survival[1][2].

 Names

Name 2-[(E)-2-(5-carbamimidoyl-1-benzofuran-2-yl)ethenyl]-1-benzofuran-5-carboximidamide,dihydrochloride
Synonym More Synonyms

 NCI 240899 Biological Activity

Description True Blue (NCI 240899) is a fluorescent dye, as neuronal retrograde tracer (excitation wavelength 395-425 nm, barrier filter 450 nm). True Blue can label neuron and has no effects on neuronal survival[1][2].
Related Catalog
In Vivo True Blue can label dorsal root ganglion neurons (DRGNs) and motoneurons (MNs) by soaking the cut sciatic nerve of adult female rats, and does not affect neuronal survival whenever 4 days or 20 weeks after soak[2].
References

[1]. M Bentivoglio, et al. Fuorescent retrograde neuronal labeling in rat by means of substances binding specifically to adenine-thymine rich DNA. Neurosci Lett. 1979 May;12(2-3):235-40.

[2]. W T Garrett, et al. Fluoro-Gold's toxicity makes it inferior to True Blue for long-term studies of dorsal root ganglion neurons and motoneurons. Neurosci Lett. 1991 Jul 8;128(1):137-9.

 Chemical & Physical Properties

Boiling Point 600.6ºC at 760 mmHg
Molecular Formula C20H18Cl2N4O2
Molecular Weight 417.28900
Flash Point 317.1ºC
Exact Mass 416.08100
PSA 126.02000
LogP 7.12160

 Safety Information

Safety Phrases 22-24/25

 Synonyms

True Blue Chloride