71431-30-6

71431-30-6 structure

Name: NCI 240899
Chemical Name: 2-[(E)-2-(5-carbamimidoyl-1-benzofuran-2-yl)ethenyl]-1-benzofuran-5-carboximidamide,dihydrochloride
CAS Number: 71431-30-6
Molecular Formula: C₂₀H₁₈Cl₂N₄O₂
Molecular Weight: 417.28900
Catalog: Research Areas Neurological Disease
Create Date: 2016-05-08 16:59:46
Modify Date: 2024-01-09 10:04:08
True Blue (NCI 240899) is a fluorescent dye, as neuronal retrograde tracer (excitation wavelength 395-425 nm, barrier filter 450 nm). True Blue can label neuron and has no effects on neuronal survival[1][2].

Name	2-[(E)-2-(5-carbamimidoyl-1-benzofuran-2-yl)ethenyl]-1-benzofuran-5-carboximidamide,dihydrochloride
Synonyms	True Blue Chloride

Description	True Blue (NCI 240899) is a fluorescent dye, as neuronal retrograde tracer (excitation wavelength 395-425 nm, barrier filter 450 nm). True Blue can label neuron and has no effects on neuronal survival[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
In Vivo	True Blue can label dorsal root ganglion neurons (DRGNs) and motoneurons (MNs) by soaking the cut sciatic nerve of adult female rats, and does not affect neuronal survival whenever 4 days or 20 weeks after soak[2].
References	[1]. M Bentivoglio, et al. Fuorescent retrograde neuronal labeling in rat by means of substances binding specifically to adenine-thymine rich DNA. Neurosci Lett. 1979 May;12(2-3):235-40. [2]. W T Garrett, et al. Fluoro-Gold's toxicity makes it inferior to True Blue for long-term studies of dorsal root ganglion neurons and motoneurons. Neurosci Lett. 1991 Jul 8;128(1):137-9.

Safety Phrases	22-24/25