8-Bromo-AMP

Modify Date: 2024-01-10 21:08:20

8-Bromo-AMP Structure
8-Bromo-AMP structure
Common Name 8-Bromo-AMP
CAS Number 23567-96-6 Molecular Weight 424.10100
Density N/A Boiling Point N/A
Molecular Formula C10H11BrN5O7P Melting Point N/A
MSDS USA Flash Point N/A

 Use of 8-Bromo-AMP


8-Bromo-AMP (8-Bromoadenosine 5'-monophosphate) is a membrane permeable cAMP analogue. 8-Bromo-AMP can improve the ability of the heart to recover from ischemia and reperfusion by increasing the levels of ATP, ADP, and total adenine nucleotides[1][2].

 Names

Name [(2R,3S,4R,5R)-5-(6-amino-8-bromopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
Synonym More Synonyms

 8-Bromo-AMP Biological Activity

Description 8-Bromo-AMP (8-Bromoadenosine 5'-monophosphate) is a membrane permeable cAMP analogue. 8-Bromo-AMP can improve the ability of the heart to recover from ischemia and reperfusion by increasing the levels of ATP, ADP, and total adenine nucleotides[1][2].
Related Catalog
References

[1]. Jiang J, et, al. Evidences for involvement of endogenous cAMP in Arabidopsis defense responses to Verticillium toxins. Cell Res. 2005 Aug;15(8):585-92.

[2]. Nakai T, et, al. Effects of adenine nucleotide analogues on myocardial dysfunction during reperfusion after ischemia in dogs. J Cardiovasc Pharmacol. 1996 Aug;28(2):264-70.

 Chemical & Physical Properties

Molecular Formula C10H11BrN5O7P
Molecular Weight 424.10100
Exact Mass 422.95800
PSA 201.54000
LogP 0.35710

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

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 Synonyms

8-Bromoadenosine 5'-phosphate
8-Bromoadenosine 5'-monophosphate
Adenosine,8-bromo-,5'-(dihydrogen phosphate) (8CI)
8-Bromo-5'-AMP
5'-Adenylic acid,8-bromo
8-Bromoadenosine 5'-(dihydrogen phosphate)
8-Bromo-AMP
8-Bromoadenylic acid