Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Eldocasiran

Eldocasiran is a micro-ARN-193a-3p analogue, Eldocasiran has anticancer activity. Eldocasiran can be used for cancer research[1].

  • CAS Number: 2615098-65-0
  • MF: C423H529N161O305P42
  • MW: 14049.50
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Glutaminase C-IN-1

Glutaminase C-IN-1 (968) is an allosteric inhibitor of Glutaminase C that inhibits cancer cell growth without affecting their normal cellular counterparts.

  • CAS Number: 311795-38-7
  • MF: C27H27BrN2O
  • MW: 475.42000
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-O-Gentiobiosyl-3,7-dimethoxy-8-hydroxyxanthone

1-O-Gentiobiosyl-3,7-dimethoxy-8-hydroxyxanthone (Compound 18) is a natural product that can be isolated from Swertia mussotii[1].

  • CAS Number: 487040-33-5
  • MF: C27H32O16
  • MW: 612.53
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Biotin-TAT (47-57)

Biotin-TAT (47-57), biotin tagged TAT, is a transactivator of transcription. Biotin-TAT (47-57) is one of the most widely used PTDs into different primary cells is ATP- and temperature-dependent, indicating the involvement of endocytosis[1][2].

  • CAS Number: 1231898-25-1
  • MF: C74H132N34O16S
  • MW: 1786.12
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Butylidenephthalide

3-Butylidenephthalide (Butylidenephthalide) is a phthalic anhydride derivative identified in Ligusticum chuanxiong Hort, and has larvicidal activity (LC50 of 1.56 mg/g for Spodoptera litura larvae)[1].

  • CAS Number: 551-08-6
  • MF: C12H12O2
  • MW: 188.223
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 312.0±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 127.9±23.4 °C

Odoratisol B

Odoratisol B is a natural product that can be isolated from Machilus odoratissima NEES[1].

  • CAS Number: 891182-94-8
  • MF: C20H24O5
  • MW: 344.40
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

GHRF, mouse

GHRF, mouse, a mouse growth hormone-releasing factor, is a peptide containing 44 amino acids. GHRF, mouse stimulates the release and synthesis of growth hormone[1].

  • CAS Number: 125199-49-7
  • MF: C220H365N69O64S
  • MW: 5032.74
  • Catalog: Endocrinology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ivangustin

Ivangustin is a sesquiterpene isolated from the flower heads of the medicinal plant Inula britannica[1].

  • CAS Number: 14164-59-1
  • MF: C15H20O3
  • MW: 248.318
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 438.0±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 187.9±21.5 °C

Boc-D-tyrosine

Boc-D-Tyr-OH is a tyrosine derivative[1].

  • CAS Number: 70642-86-3
  • MF: C14H19NO5
  • MW: 281.304
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 484.9±40.0 °C at 760 mmHg
  • Melting Point: 135-140 °C
  • Flash Point: 247.1±27.3 °C

Olmesartan ethyl ester

Olmesartan ethyl ester (compound 11) is an Olmesartan impurity. Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist used to in the high blood pressure study[1].

  • CAS Number: 144689-23-6
  • MF: C26H30N6O3
  • MW: 474.55500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BIBR 1087 SE

BIBR 1087 SE is an intermediate metabolite of dabigatran etexilate.

  • CAS Number: 212321-78-3
  • MF: C32H37N7O5
  • MW: 599.680
  • Catalog: Inflammation/Immunology
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 853.4±75.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 469.9±37.1 °C

MoTP

MoTP is a specific platelet activating factor receptor antagonist and can induce melanocyte ablation. MoTP can be used for the research of cancer.

  • CAS Number: 57055-82-0
  • MF: C14H21NO2S
  • MW: 267.387
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 424.9±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 210.8±27.3 °C

Raloxifene-d10-1

Raloxifene-d10-1 is the deuterium labeled Raloxifene[1]. Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and osteoporosis research[2].

  • CAS Number: 2512224-37-0
  • MF: C28H17D10NO4S
  • MW: 483.64
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Potassium tert-butyl malonate

Potassium tert-butyl malonate is an intermediate in the synthesis of malonate monoester potassium salt[1].

  • CAS Number: 75486-33-8
  • MF: C7H11KO4
  • MW: 198.26
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Eburicoic acid

Eburicoic acid protects the liver from CCl4-induced hepatic damage via antioxidant and anti-inflammatory mechanisms[1]. And Eburicoic acid has antidiabetic and antihyperlipidemic effects[2].

  • CAS Number: 560-66-7
  • MF: C31H50O3
  • MW: 470.73
  • Catalog: Cardiovascular Disease
  • Density: 1.05g/cm3
  • Boiling Point: 572.6ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 314.1ºC

5-Hydroxy-4',7-dimethoxy-6,8-dimethylflavone

Eucalyptin is a flavonoid. Eucalyptin can be isolated from Myrcia citrifolia[1].

  • CAS Number: 3122-88-1
  • MF: C19H18O5
  • MW: 326.343
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 539.5±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 196.4±23.6 °C

PF-184298

PF-184298 is a potent, selective dual serotonin and noradrenaline monoamine reuptake inhibitor (SNRI) with IC50 of 6 nM and 21 nM, respectively; displays good selectivity over dopamine reuptake inhibition (DRI) (IC50=544 nM); possesses good in vitro metabolic stability, weak CYP inhibition and drug-like physicochemical properties consistent with CNS target space.

  • CAS Number: 813447-40-4
  • MF: C15H20Cl2N2O
  • MW: 315.238
  • Catalog: Cardiovascular Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 461.9±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 233.1±28.7 °C

BOC-GLU(OBZL)-GLY-ARG-MCA HYDROCHLORIDE

Boc-Glu(OBzl)-Gly-Arg-AMC is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 73554-94-6
  • MF: C35H45N7O9
  • MW: 707.77
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(2R,3S,5R)-5-(4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol

4-Chloro-7-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects[1].

  • CAS Number: 178995-71-6
  • MF: C11H11ClIN3O3
  • MW: 395.58100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Acetylexidonin

Acetylexidonin is a diterpenoid compound with anti-inflammation and cancer activity. Acetylexidonin inhibits tumor cells with IC50s of 3.69 μM (NB4) and 26.22 μM (SHSY5Y), respectively[1].

  • CAS Number: 116368-90-2
  • MF: C26H34O9
  • MW: 490.543
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 615.4±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 261.7±31.5 °C

Phenylthiocarbamide

Phenylthiourea (Phenylthiocarbamide) is an inhibitor of phenoloxidase. Phenylthiourea inhibits enzymatic oxidation of DOPA by phenoloxidase (Ki: 0.21?μM)[1].

  • CAS Number: 103-85-5
  • MF: C7H8N2S
  • MW: 152.217
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 266.7±23.0 °C at 760 mmHg
  • Melting Point: 145-150 °C(lit.)
  • Flash Point: 115.1±22.6 °C

sodium cyanoborodeuteride

Sodium cyanoboronhydride-d3 is the deuterium labeled Sodium cyanoboronhydride[1].

  • CAS Number: 25895-62-9
  • MF: CBD3NNa
  • MW: 65.86050
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: >242ºC (dec.)(lit.)
  • Flash Point: N/A

ACTH (1-13)

ACTH (1-13) is a 13-aa peptide, with cytoprotective effects in the model of ethanol induced gastric lesions in rats.

  • CAS Number: 22006-64-0
  • MF: C75H106N20O19S
  • MW: 1623.83000
  • Catalog: Peptides
  • Density: 1.49g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sodium Glycinate

Sodium 2-aminoacetate is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 6000-44-8
  • MF: C2H4NNaO2
  • MW: 97.048
  • Catalog: Others
  • Density: 1.014g/cm3
  • Boiling Point: 240.9ºC at 760 mmHg
  • Melting Point: 290ºC decomposes
  • Flash Point: 99.5ºC

Thymidine diphosphate-L-rhamnose

Thymidine-5'-diphosphate-L-rhamnose disodium can be isolated from Occhromonas malhamensis[1].

  • CAS Number: 2147-59-3
  • MF: C16H26N2O15P2
  • MW: 548.330
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Z-D-Dbu(N3)-OH

Z-D-Dbu(N3)-OH is a click chemistry reagent containing an azide group. Z-D-Dbu(N3)-OH can be used for the research of various biochemical[1].

  • CAS Number: 1931958-82-5
  • MF: C12H14N4O4
  • MW: 278.26
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PBB3

PBB3, a selective PET ligand, recognizes tau pathology in Alzheimer's disease brains, where dystrophic neurites and diffuse neurofibrils are more clearly detected Tangles with calcification[1].

  • CAS Number: 1565796-97-5
  • MF: C17H15N3OS
  • MW: 309.39
  • Catalog: Neurological Disease
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 572.4±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 300.0±32.9 °C

FATP1-IN-2

FATP1-IN-2, as an arylpiperazine derivative, is an orally active fatty acid transport protein 1 (FATP1) inhibitor (human IC50=0.43 μM, mouse IC50=0.39 μM)[1].

  • CAS Number: 2650944-83-3
  • MF: C19H20FN5O
  • MW: 353.39
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

6-Chloro-1H-indol-3-yl β-D-galactopyranoside

Rose-β-D-Gal is a flurescent dye, is also a β-galactosidase substrate. Rose-β-D-Gal creates a pink/magenta color after the reaction and has been used for detection of β-gal activity[1][2].

  • CAS Number: 138182-21-5
  • MF: C14H16ClNO6
  • MW: 329.733
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 630.2±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 335.0±31.5 °C

Glyoxalase I inhibitor 4

Glyoxalase I inhibitor 4 (compound 14) is a potent glyoxalase I inhibitor with an Ki of 10 nM[1].

  • CAS Number: 250155-72-7
  • MF: C17H21IN4O8S
  • MW: 568.34
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A