FATP1-IN-2
Modify Date: 2025-08-24 19:08:31
FATP1-IN-2 structure
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Common Name | FATP1-IN-2 | ||
|---|---|---|---|---|
| CAS Number | 2650944-83-3 | Molecular Weight | 353.39 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H20FN5O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of FATP1-IN-2FATP1-IN-2, as an arylpiperazine derivative, is an orally active fatty acid transport protein 1 (FATP1) inhibitor (human IC50=0.43 μM, mouse IC50=0.39 μM)[1]. |
| Name | FATP1-IN-2 |
|---|
| Description | FATP1-IN-2, as an arylpiperazine derivative, is an orally active fatty acid transport protein 1 (FATP1) inhibitor (human IC50=0.43 μM, mouse IC50=0.39 μM)[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 0.43 μM (human FATP1)[1]. IC50: 0.39 μM (mouse FATP1)[1] |
| In Vivo | FATP1-IN-2 (10 mg/kg; p.o.) shows a Cmax value above the mouse IC50 value[1]. FATP1-IN-2 (3, 10, 30 mg/kg; p.o.; 4 weeks) shows TG content of each tissue does not change at any dose[1]. Animal Model: Mice[1] Dosage: 10 mg/kg Administration: P.o. Result: Showed a Cmax value above the mouse IC50 value. |
| References |
| Molecular Formula | C19H20FN5O |
|---|---|
| Molecular Weight | 353.39 |
| InChIKey | ZGLMIQGBDRQCKA-UHFFFAOYSA-N |
| SMILES | Cc1nc2ccccn2c1C(=O)CN1CCN(c2ccc(F)cn2)CC1 |