1386980-04-6
1386980-04-6 structure
- Name: DYRKs-IN-2
- Chemical Name: DYRKs-IN-2
- CAS Number: 1386980-04-6
- Molecular Formula: C32H38ClN9O3
- Molecular Weight: 632.16
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK DYRK
- Create Date: 2019-12-08 17:25:19
- Modify Date: 2024-01-10 10:30:02
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DYRKs-IN-2 (Example 132) is a potent DYRKs inhibitor with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively. DYRKs-IN-2 has antitumor activity[1].
| Name | DYRKs-IN-2 |
|---|
| Description | DYRKs-IN-2 (Example 132) is a potent DYRKs inhibitor with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively. DYRKs-IN-2 has antitumor activity[1]. |
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| Related Catalog | |
| Target |
IC50: 30.6 nM (DYRK1B) and 12.8 nM (DYRK1A)[2] |
| In Vitro | DYRKs-IN-2 (Example 132) has an EC50 of 22.8 nM for SW620 cell line[1]. |
| References |
[1]. Kevin Anderson, et al. Pyrido pyrimidines. US20120184542A1 |
| Molecular Formula | C32H38ClN9O3 |
|---|---|
| Molecular Weight | 632.16 |