FATP1-IN-1

Modify Date: 2025-08-25 14:32:10

FATP1-IN-1 Structure
FATP1-IN-1 structure
Common Name FATP1-IN-1
CAS Number 1431945-95-7 Molecular Weight 375.46
Density N/A Boiling Point N/A
Molecular Formula C18H22FN5OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FATP1-IN-1


FATP1-IN-1 is a fatty acid transport protein 1 (FATP1) inhibitor. FATP1-IN-1 is an inhibition of recombinant human or mouse acyl-CoA synthetase activity of FATP1, with the IC50 values of 0.046 μM or 0.60 μM, respectively[1].

 Names

Name FATP1-IN-1

 FATP1-IN-1 Biological Activity

Description FATP1-IN-1 is a fatty acid transport protein 1 (FATP1) inhibitor. FATP1-IN-1 is an inhibition of recombinant human or mouse acyl-CoA synthetase activity of FATP1, with the IC50 values of 0.046 μM or 0.60 μM, respectively[1].
Related Catalog
In Vivo FATP1-IN-1 (p.o.; 10 mg/kg) treatment shows the Cmax, AUC and Tmax were 5.5 μg/mL, 36 μg h/mL and 0.33 hours, respectively, and exceeds the mouse IC50 value of 0.22 μM without considering plasma protein binding. Animal Model: Mouse plasma[1] Dosage: 10 mg/kg Administration: P.o. Result: The Cmax, AUC and Tmax were 5.5 μg/mL, 36 μg h/mL and 0.33 hours, respectively.
References

[1]. Matsufuji T, et al. Arylpiperazines as fatty acid transport protein 1 (FATP1) inhibitors with improved potency and pharmacokinetic properties. Bioorg Med Chem Lett. 2013;23(9):2560-2565.

 Chemical & Physical Properties

Molecular Formula C18H22FN5OS
Molecular Weight 375.46

 Safety Information

Hazard Codes Xi
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.