Name | FATP1-IN-1 |
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Description | FATP1-IN-1 is a fatty acid transport protein 1 (FATP1) inhibitor. FATP1-IN-1 is an inhibition of recombinant human or mouse acyl-CoA synthetase activity of FATP1, with the IC50 values of 0.046 μM or 0.60 μM, respectively[1]. |
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Related Catalog | |
In Vivo | FATP1-IN-1 (p.o.; 10 mg/kg) treatment shows the Cmax, AUC and Tmax were 5.5 μg/mL, 36 μg h/mL and 0.33 hours, respectively, and exceeds the mouse IC50 value of 0.22 μM without considering plasma protein binding. Animal Model: Mouse plasma[1] Dosage: 10 mg/kg Administration: P.o. Result: The Cmax, AUC and Tmax were 5.5 μg/mL, 36 μg h/mL and 0.33 hours, respectively. |
References |
Molecular Formula | C18H22FN5OS |
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Molecular Weight | 375.46 |
Hazard Codes | Xi |
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