Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Perakine

Perakine is an indole alkaloid isolated from Alstonia yunnanensis. Anti-inflammatory activities[1].

  • CAS Number: 4382-56-3
  • MF: C21H22N2O3
  • MW: 350.411
  • Catalog: Inflammation/Immunology
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 492.8±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 251.9±28.7 °C

Z-Ile-Pro-OH

Cbz-Ile-Pro-OH (NSC 333754) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 13211-37-5
  • MF: C19H26N2O5
  • MW: 362.42
  • Catalog: Others
  • Density: 1.224g/cm3
  • Boiling Point: 588.7ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 309.8ºC

M700F048

M700F048 is a metabolite of soybean seeds[1].

  • CAS Number: 2056235-51-7
  • MF: C23H20F5N3O6
  • MW: 529.41
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cyanine3 azide chloride

Cyanine3 azide chloride, an analog of Cy3 azide, is a potent green fluorescent dye. Cyanine3 azide chloride uses click chemistry coupled with Alkyne-labeled proteins. Cyanine3 azide chloride can be detected by fluorometers, imagers, and microscopes. (λex=684 nm, λem=710 nm)[1][2]>.

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Saponins

Saponins are a class of chemical compounds of glycosides found in particular abundance in various plant species. In plants, saponins may serve as anti-feedants, and to protect the plant against microbes and fungi[1].

  • CAS Number: 8047-15-2
  • MF: C27H42O3
  • MW: 1645.293
  • Catalog: Inflammation/Immunology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 158℃
  • Flash Point: N/A

Amino(2-thienyl)acetic acid

(S)-2-Amino-2-(thiophen-2-yl)acetic acid is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 43189-45-3
  • MF: C6H7NO2S
  • MW: 157.190
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 311.8±32.0 °C at 760 mmHg
  • Melting Point: 142-146 °C
  • Flash Point: 142.4±25.1 °C

1,2,3,4,6-O-Pentagalloylglucose

1,2,3,4,6-Penta-O-galloyl-β-D-glucopyranose is a gallotannin isolated from various plants. It suppressed interleukin (IL)-4 induced signal pathway in B cell, and inhibited IgE production partially caused by increasing a population of Treg cells in conjunction with Treg-inducing factors.

  • CAS Number: 14937-32-7
  • MF: C41H32O26
  • MW: 940.677
  • Catalog: Others
  • Density: 2.1±0.1 g/cm3
  • Boiling Point: 1365.7±65.0 °C at 760 mmHg
  • Melting Point: >250ºC dec.
  • Flash Point: 410.4±27.8 °C

Fmoc-N-Me-Ala-OH

Fmoc-N-Me-Ala-OH, an N-Fmoc-N-methyl amino acid, is available for the peptide-coupling reaction.

  • CAS Number: 84000-07-7
  • MF: C19H19NO4
  • MW: 325.358
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 514.9±29.0 °C at 760 mmHg
  • Melting Point: ~150 °C
  • Flash Point: 265.2±24.3 °C

Cymarin

Cymarin, a cardiac glycoside, potently inhibits the Palytoxin (PTX)-induced K+ release (IC50=0.42 μM)[1].

  • CAS Number: 508-77-0
  • MF: C30H44O9
  • MW: 548.66
  • Catalog: Others
  • Density: 1.31 g/cm3
  • Boiling Point: 722.1ºCat 760 mmHg
  • Melting Point: 148ºC
  • Flash Point: 232.7ºC

3-O-Feruloylquinic acid

3-Feruloylquinic acid, a derivative of quinic acid-bound phenolic acid, shows antioxidant activity. 3-Feruloylquinic acid markedly enhances by high photosynthetically active radiation (PAR) and UV irradiances[1][2].

  • CAS Number: 1899-29-2
  • MF: C17H20O9
  • MW: 368.33500
  • Catalog: Others
  • Density: 1.53g/cm3
  • Boiling Point: 629.4ºC at 760 mmHg
  • Melting Point: 196-197 ºC
  • Flash Point: 228.6ºC

Talizumab

Talizumab (TNX 901) is an anti-IgE humanized IgG1 monoclonal antibody[1].

  • CAS Number: 380610-22-0
  • MF:
  • MW:
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Prolylleucine

Prolylleucine is a dipeptide containing branched-chain amino acids.

  • CAS Number: 61596-47-2
  • MF: C19H26N2O5
  • MW: 362.42000
  • Catalog: Peptides
  • Density: 1.224g/cm3
  • Boiling Point: 593.7ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 312.9ºC

β-Amyloid (1-38), mouse, rat

β-Amyloid (1-38), mouse, rat is composed of 38 aa (1-38 residues of the Aβ peptide) and is the primary component of the amyloid plaques of Alzheimer’s disease[1].

  • CAS Number: 186359-66-0
  • MF: C180H273N49O55S1
  • MW: 4035.50
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

12R-LOX-IN-1

12R-LOX-IN-1 (Compound 4a) is a 12R-LOX inhibitor (IC50: 28.25 μM). 12R-LOX-IN-1 inhibits the hyper-proliferative state and colony forming potential of Imiquimod (HY-B0180)-induced psoriatic keratinocytes. 12R-LOX-IN-1 inhibits reactive oxygen species, Ki67, IL-17A, TNF-α and IL-6 production. 12R-LOX-IN-1 can be used for antipsoriatic research[1].

  • CAS Number: 857758-13-5
  • MF: C15H11NO2
  • MW: 237.25
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CP742033

CP742033 is a gut-selective inhibitor of microsomal triglyceride transfer protein (MTP) that reliably produces weight loss in obese dogs.

  • CAS Number: 481658-94-0
  • MF: C40H33F3N4O3
  • MW: 674.710
  • Catalog: Metabolic Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 821.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 450.5±34.3 °C

H-Leu-Ser-OH

H-Leu-Ser-OH is a dipeptide formed from L-leucine and L-serine residues and is a metabolite[1].

  • CAS Number: 6209-12-7
  • MF: C9H18N2O4
  • MW: 218.25000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TAPS (buffer)

TAPS is a biological buffer, remain lysozyme native structure intact and prevents thermal denaturation against high temperatures. TAPS exhibits pKa value of 8.1, while the half-maximum values of connexin channel activity is 8.5 (pH)[1][2].

  • CAS Number: 29915-38-6
  • MF: C7H17NO6S
  • MW: 243.278
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 230-235 °C (dec.)
  • Flash Point: 110 °C

N3-L-Dab(Boc)-OH

N3-L-Dab(Boc)-OH is a click chemistry reagent containing an azide group. N3-L-Dab(Boc)-OH can be used for the research of various biochemical[1].

  • CAS Number: 1932403-71-8
  • MF: C9H16N4O4
  • MW: 244.25
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Demoxepam

Demoxepam is a major metabolite of Chlordiazepoxide. Demoxepam exhibits cytotoxicity activity against cancer cell lines. Demoxepam has anticonvulsant and anxiolytic effects[1][2].

  • CAS Number: 963-39-3
  • MF: C15H11ClN2O2
  • MW: 286.71300
  • Catalog: Neurological Disease
  • Density: 1.37g/cm3
  • Boiling Point: 447.4ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 224.4ºC

H-Pro-Leu-OH

(S)-4-Methyl-2-((S)-pyrrolidine-2-carboxamido)pentanoic acid is a leucine derivative[1].

  • CAS Number: 52899-07-7
  • MF: C11H20N2O3
  • MW: 228.28800
  • Catalog: Others
  • Density: 1.126g/cm3
  • Boiling Point: 457.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 230.5ºC

Guacetisal

Guacetisal is obtained from the esterification of acetylsalicylic acid with guaiacol which can be used to treat chronic bronchitis extracted from patent CN 106866420 A.

  • CAS Number: 55482-89-8
  • MF: C16H14O5
  • MW: 286.279
  • Catalog: Inflammation/Immunology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 463.8±30.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 207.2±24.6 °C

Alisol A

Alisol A is a natural product.

  • CAS Number: 19885-10-0
  • MF: C30H50O5
  • MW: 490.715
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 629.3±55.0 °C at 760 mmHg
  • Melting Point: 90-91ºC
  • Flash Point: 348.4±28.0 °C

Thiotraniliprole

Thiotraniliprole (HY366) is an ortho formamidobenzamide insecticide that can be used for the synthesis of insecticidal combinations. Thiotraniliprole has potential applications in the prevention of lepidoptera pests, coleoptera pests, ants, and termites[1][2].

  • CAS Number: 1442448-92-1
  • MF: C19H15BrCl3N5OS
  • MW: 547.68
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Chlorophenylacetic acid

4-Chlorophenylacetic acid is a compound belongs to a family of small aromatic fatty acids with anticancer properties. 4-Chlorophenylacetic acid can provide carbon and energy for Pseudomonas sp[1][2].

  • CAS Number: 1878-66-6
  • MF: C8H7ClO2
  • MW: 170.593
  • Catalog: Metabolic Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 294.1±15.0 °C at 760 mmHg
  • Melting Point: 102-105 °C(lit.)
  • Flash Point: 131.7±20.4 °C

Biotin N-(bromoacetyl)hydrazide

Biotin N-(bromoacetyl)hydrazide is a biotin derivative[1].

  • CAS Number: 57170-18-0
  • MF: C12H19BrN4O3S
  • MW: 379.27
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Secoisolariciresinol

Secoisolariciresinol, isolated from water extract of silver fir (Abies alba) wood, is a lignan, a type of phenylpropanoids.

  • CAS Number: 29388-59-8
  • MF: C20H26O6
  • MW: 362.417
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 609.1±55.0 °C at 760 mmHg
  • Melting Point: 112-114ºC
  • Flash Point: 322.1±31.5 °C

CAM741

CAM741 is a selective VCAM-1 translocation inhibitor. CAM741 selectively inhibits VCAM-1 expression by inhibiting its co-translational translocation within the lumen of the endoplasmic reticulum (ER). CAM741 can be used as a molecular tool and can also be used in the research of chronic inflammation and cancer[1][2].

  • CAS Number: 177586-74-2
  • MF: C56H91N7O11
  • MW: 1038.36
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hyaluronan-IN-1

Hyaluronan-IN-1 is a biological active peptide. (This 12 amino acids peptide is a hyaluronan inhibitor (HA), a high molecular weight glycosaminoglycan expressed abundantly in the extracellular matrix and on cell surfaces. This peptide shows specific binding to soluble, immobilized, and cell-associated forms of HA, and it inhibits leukocyte adhesion to HA substrates almost completely.)

  • CAS Number: 299157-43-0
  • MF: C64H94N20O16
  • MW: 1399.56
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

D-Histidine hydrochloride monohydrate

D-Histidine monohydrochloride monohydrate is a histidine derivative[1].

  • CAS Number: 6341-24-8
  • MF: C6H10ClN3O2
  • MW: 191.61500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 254ºC (dec.)(lit.)
  • Flash Point: N/A

Angiogenin (108-123)

Angiogenin Fragment (108-123) is a C-terminal segment 108-123 of Angiogenin that inhibits the enzymatic and biological activities of Angiogenin[1].

  • CAS Number: 112173-48-5
  • MF: C83H132N26O24
  • MW: 1878.10000
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A