112173-48-5

112173-48-5 structure

Name: Angiogenin (108-123)
Chemical Name: Angiogenin Fragment (108-123)
CAS Number: 112173-48-5
Molecular Formula: C₈₃H₁₃₂N₂₆O₂₄
Molecular Weight: 1878.10000
Catalog: Research Areas Cardiovascular Disease
Create Date: 2018-12-18 18:32:57
Modify Date: 2024-01-11 12:04:28
Angiogenin Fragment (108-123) is a C-terminal segment 108-123 of Angiogenin that inhibits the enzymatic and biological activities of Angiogenin[1].

Name	Angiogenin Fragment (108-123)
Synonyms	angiogenin fragment 108-123 glu-asn-gly-leu-pro-val-his-leu-asp-gln-ser-ile-phe-arg-arg-pro angiogenin (108-123) h-glu-asn-gly-leu-pro-val-his-leu-asp-gln-ser-ile-phe-arg-arg-pro-oh

Description	Angiogenin Fragment (108-123) is a C-terminal segment 108-123 of Angiogenin that inhibits the enzymatic and biological activities of Angiogenin[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
In Vitro	Angiogenin Fragment (108-123) inhibits the initial rate of degradation of tRNA catalyzed by angiogenin in a concentration dependent manner yielding an apparent Ki value of 278 μM. Angiogenin Fragment (108-123) also inhibits nuclease activity of angiogenin when tRNA is the substrate. Furthermore, Angiogenin Fragment (108-123) significantly decreases neovascularization elicited by angiogenin in the chick chorioallantoic membrane assay[1].
References	[1]. S M Rybak, et al. C-terminal angiogenin peptides inhibit the biological and enzymatic activities of angiogenin. Biochem Biophys Res Commun. 1989 Jul 14;162(1):535-43.