29915-38-6

29915-38-6 structure

Name: TAPS (buffer)
Chemical Name: 3-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]propane-1-sulfonic acid
CAS Number: 29915-38-6
Molecular Formula: C₇H₁₇NO₆S
Molecular Weight: 243.278
Catalog: Chemical reagent Organic reagent Sulfonic acid/sulfinic acid
Create Date: 2018-03-22 08:00:00
Modify Date: 2024-01-02 18:45:36
TAPS is a biological buffer, remain lysozyme native structure intact and prevents thermal denaturation against high temperatures. TAPS exhibits pKa value of 8.1, while the half-maximum values of connexin channel activity is 8.5 (pH)[1][2].

Name	3-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]propane-1-sulfonic acid
Synonyms	1-Propanesulfonic acid, 3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]- [(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid 3-((1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl)amino)propane-1-sulfonic acid N-Tris(Hydroxymethy)methyl-3-aminopropanesulfonic acid T3A 3-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}propane-1-sulfonic acid N-Tris(hydroxymethyl)methyl-3-aminopropanesulfonic Acid [Good's buffer component EINECS 249-954-1 N-[Tris（hydroxymethyl）metyl]-3-aminopropanesulfonic acid 3-(TRIS(HYDROXYMETHYL)METHYLAMINO)-1-PROPANESULFONIC ACID 3-{[1,3-Dihydroxy-2-(hydroxymethyl)-2-propanyl]amino}-1-propanesulfonic acid MFCD00007538 TAPS 3-[N-Tris-(hydroxymethyl)methylamino]propanesulphonic (TAPS) N-Tris(hydroxymethyl)methyl-3-aminopropanesulfonic acid

Description	TAPS is a biological buffer, remain lysozyme native structure intact and prevents thermal denaturation against high temperatures. TAPS exhibits pKa value of 8.1, while the half-maximum values of connexin channel activity is 8.5 (pH)[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Pannuru P, et al. The effects of biological buffers TRIS, TAPS, TES on the stability of lysozyme. Int J Biol Macromol. 2018 Jun;112:720-727. [2]. Bevans CG, et al. Regulation of connexin channels by pH. Direct action of the protonated form of taurine and other aminosulfonates. J Biol Chem. 1999 Feb 5;274(6):3711-9.Bevans CG, et al. Regulation of connexin channels by pH. Direct action of the protonated form of taurine and other aminosulfonates. J Biol Chem. 1999 Feb 5;274(6):3711-9.

Density	1.5±0.1 g/cm3
Melting Point	230-235 °C (dec.)
Molecular Formula	C₇H₁₇NO₆S
Molecular Weight	243.278
Flash Point	110 °C
Exact Mass	243.077652
PSA	135.47000
LogP	-2.40
Index of Refraction	1.561
Storage condition	Store at RT.
Stability	Stable. Incompatible with strong oxidizing agents
Water Solubility	Soluble

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Risk Phrases	R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	29221980

1120-71-4

77-86-1

29915-38-6

Literature: Justus Liebigs Annalen der Chemie, , p. 667 - 670

Precursor 2
1120-71-4 77-86-1
DownStream 0

HS Code	29221980