12R-LOX-IN-1

12R-LOX-IN-1 structure	Common Name	12R-LOX-IN-1
	CAS Number	857758-13-5	Molecular Weight	237.25
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₁₁NO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 12R-LOX-IN-1

12R-LOX-IN-1 (Compound 4a) is a 12R-LOX inhibitor (IC50: 28.25 μM). 12R-LOX-IN-1 inhibits the hyper-proliferative state and colony forming potential of Imiquimod (HY-B0180)-induced psoriatic keratinocytes. 12R-LOX-IN-1 inhibits reactive oxygen species, Ki67, IL-17A, TNF-α and IL-6 production. 12R-LOX-IN-1 can be used for antipsoriatic research[1].

Name	12R-LOX-IN-1

Description	12R-LOX-IN-1 (Compound 4a) is a 12R-LOX inhibitor (IC50: 28.25 μM). 12R-LOX-IN-1 inhibits the hyper-proliferative state and colony forming potential of Imiquimod (HY-B0180)-induced psoriatic keratinocytes. 12R-LOX-IN-1 inhibits reactive oxygen species, Ki67, IL-17A, TNF-α and IL-6 production. 12R-LOX-IN-1 can be used for antipsoriatic research[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Bhuktar H, et al. Design, synthesis and evaluation of 2-aryl quinoline derivatives against 12R-lipoxygenase (12R-LOX): Discovery of first inhibitor of 12R-LOX. Bioorg Chem. 2023 Sep;138:106606.

Molecular Formula	C₁₅H₁₁NO₂
Molecular Weight	237.25

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12R-LOX-IN-1

Use of 12R-LOX-IN-1

Names

12R-LOX-IN-1 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.