Coniferaldehyde (Ferulaldehyde), isolated from the ethanol extract of Vitex rotundifolia fruits, is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde exerts anti-inflammatory properties in response to LPS. Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells[1].
(±)-ErSO is the racemate of ErSO. ErSO is a selective anticipatory unfolded protein response (a-UPR) activator[1].
N-3-Oxo-octanoyl-L-homoserine lactone, a quorum-sensing signal, is an Agrobacterium autoinducer[1][2].
3-(Dansylamino)phenylboronic acid, a phenylboronic acid derivative, can be used for the glucose detection[1].
Thevetin B (compound 1) is a betalain isolated from Thevetia peruviana[1].
Spiranthesol is an active compound. Spiranthesol can be isolated from the aerial parts of Spiranthes sinensis(Pers.) [1].
5-Deoxystrigol is a potent striga germination stimulant[1].
Acetic acid-d3 is a the deuterium labeled Acetic acid (HY-Y0319) [1].
2-Acetamidofluorene is a potent carcinogenan. 2-Acetamidofluorene is can be used fot induction of hepatocellular carcinoma (HCC) and multiple primary tumours[1][2].
GIP (1-39) (Gastric inhibitory peptide (1-39) (porcine)) is an insulinotropic peptide that stimulats insulin secretion from rat pancreatic islets. GIP (1-39) at 100 nM was able to significantly increase intracellular Ca2+ concentration ([Ca2+]i), and capable of enhancing exocytosis[1].
Allitol is a rare natural polyol that can be used as a sweetener. Allitol is an important intermediate for the preparation of the agents which against diabetes, cancer, and viral infections, including AIDS[1].
DL-Goitrin, also called (R, S)- report by the spring, consists of the epigoitrin (reported by the R- Spring) and the spring (-S- reported by spring), and the two mutually isomers, and the mixture is the ingredient of Radix[1].
Tiragolumab is an immune checkpoint inhibitor binding to T-cell immunoglobulin and ITIM domain (TIGIT). Tiragolumab, alone or in combination with the PD-L1 inhibitor Atezolizumab, may be effective against multiple solid malignancies-most notably non-small cell lung cancer[1][2].
Ala-Ala-Pro-pNA is a tripeptide, including chromophoric amino acids Pro-pNA. Ala-Ala-Pro-pNA is targeted by tripeptidyl aminopeptidase (SM-TAP)[1].
Seletracetam (Ucb 44212) is an analog of the antiepileptic agent Levetiracetam. Seletracetam is a small molecule SV2A modulator for the research of epilepsy[1][2][3].
Biotinoyl tripeptide-1 (Biotinyl-GHK; Bio-GHK)is a bioactive peptide with hair growth effect and has been reported used as a cosmetic ingredient[1].
4-(Trifluoromethyl)benzoic acid-13C6 is the 13C labeled 4-(Trifluoromethyl)benzoic acid[1].
Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) amide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].
(R)-Necrocide 1 (compound (R)-38) a potent anticancer agent. (R)-Necrocide 1 has antiproliferative activity[1].
Yibeinoside A is an alkaloid isolated from the bulb of Fritillaria pallidiflora Schreb [1].
Globotriaosylsphingosine (lyso-Gb3) inhibits the growth of fibroblasts, as well as their differentiation into myofibroblasts, and collagen expression. Globotriaosylsphingosine can be used for Fabry disease research[1].
Ucasareotide dasaroxetan (SarTATE) is diagnostic agent with antineoplastic effect[1].
Mulberrin is a strong inhibitor of organic anion-transporting polypeptide 2B1 (OATP2B1)-mediated estrone-3-sulfate (E3S) uptake with an IC50 value being 1.8 ±1.5 μM.
HS-38 is a potent and selective DAPK1 and DAPK3 (ZIPK) inhibitor with IC50 of 200 nM for DAPK1 and Kd of 280 nM for ZIPK, also inhibits Pim3 (IC50=200 nM), and displays no activity against Src or Abl, little activity against EGFR; decreases RLC20 phosphorylation in cells, and decreases contractile force generated in mouse aorta, rabbit ileum, and calyculin A stimulated arterial muscle by decreasing RLC20 and MYPT1 phosphorylation; also promotes relaxation in Ca(2+)-sensitized vessels.
L-Proline β-naphthylamide (hydrochloride) is a proline derivative[1].
Ethyl everninate is an atranol-like secondary metabolite that can be isolated from oakmoss[1].
pentadecanoate-d29 is the deuterium labeled pentadecanoate.
Bz-DTPA is a bifunctional chelator. Bz-DTPA can be used for preparing immunoconjugate of monoclonal antibody 2G3 labeled with indium-111[1].