1-(4-isothiocyanatobenzyl)diethylenetriaminepentaacetic acid

Modify Date: 2024-01-09 10:24:13

1-(4-isothiocyanatobenzyl)diethylenetriaminepentaacetic acid Structure
1-(4-isothiocyanatobenzyl)diethylenetriaminepentaacetic acid structure
Common Name 1-(4-isothiocyanatobenzyl)diethylenetriaminepentaacetic acid
CAS Number 102650-30-6 Molecular Weight 540.54
Density 1.43g/cm3 Boiling Point 858.8ºC at 760mmHg
Molecular Formula C22H28N4O10S Melting Point N/A
MSDS N/A Flash Point 473.2ºC

 Use of 1-(4-isothiocyanatobenzyl)diethylenetriaminepentaacetic acid


Bz-DTPA is a bifunctional chelator. Bz-DTPA can be used for preparing immunoconjugate of monoclonal antibody 2G3 labeled with indium-111[1].

 Names

Name 2-[2-[bis(carboxymethyl)amino]ethyl-[(2S)-2-[bis(carboxymethyl)amino]-3-(4-isothiocyanatophenyl)propyl]amino]acetic acid
Synonym More Synonyms

  Biological Activity

Description Bz-DTPA is a bifunctional chelator. Bz-DTPA can be used for preparing immunoconjugate of monoclonal antibody 2G3 labeled with indium-111[1].
Related Catalog
References

[1]. Reilly R, et, al. In vitro stability of EDTA and DTPA immunoconjugates of monoclonal antibody 2G3 labeled with indium-111. Int J Rad Appl Instrum A. 1992 Aug;43(8):961-7.  

 Chemical & Physical Properties

Density 1.43g/cm3
Boiling Point 858.8ºC at 760mmHg
Molecular Formula C22H28N4O10S
Molecular Weight 540.54
Flash Point 473.2ºC
Exact Mass 540.15300
PSA 240.67000
Vapour Pressure 1.99E-31mmHg at 25°C
Index of Refraction 1.619

 Synonyms

Glycine,N-(2-((2-(bis(carboxymethyl)amino)ethyl)(carboxymethyl)amino)-1-((4-isothiocyanatophenyl)methyl)ethyl)-N-(carboxymethyl)-,(S)
1-(4-Isothiocyanatobenzyl)diethylenetriaminepentaacetic acid
Scn-Bz-dtpa
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