126550-86-5

126550-86-5 structure

Name: Lyso-Globotriaosylceramide (d18:1)
Chemical Name: Globotriaosylsphingosine from porcine blood
CAS Number: 126550-86-5
Molecular Formula: C₃₆H₆₇NO₁₇
Molecular Weight: 785.91400
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
Create Date: 2018-11-30 17:57:32
Modify Date: 2025-08-23 22:10:08
Globotriaosylsphingosine (lyso-Gb3) inhibits the growth of fibroblasts, as well as their differentiation into myofibroblasts, and collagen expression. Globotriaosylsphingosine can be used for Fabry disease research[1].

Name	Globotriaosylsphingosine from porcine blood
Synonyms	(2S,3R,4E)-2-Amino-3-hydroxy-4-octadecen-1-yl α-D-galactopyranosyl-(1->4)-β-D-galactopyranosyl-(1->4)-β-D-glucopyranoside

Description	Globotriaosylsphingosine (lyso-Gb3) inhibits the growth of fibroblasts, as well as their differentiation into myofibroblasts, and collagen expression. Globotriaosylsphingosine can be used for Fabry disease research[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Choi JY, et al. Lyso-globotriaosylceramide downregulates KCa3.1 channel expression to inhibit collagen synthesis in fibroblasts. Biochem Biophys Res Commun. 2015 Dec 25;468(4):883-8. [2]. Auray-Blais C, et al. How well does urinary lyso-Gb3 function as a biomarker in Fabry disease? Clin Chim Acta. 2010 Dec 14;411(23-24):1906-14.

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