coniferyl aldehyde

Modify Date: 2024-01-03 01:32:37

coniferyl aldehyde Structure
coniferyl aldehyde structure
Common Name coniferyl aldehyde
CAS Number 458-36-6 Molecular Weight 178.185
Density 1.2±0.1 g/cm3 Boiling Point 338.8±27.0 °C at 760 mmHg
Molecular Formula C10H10O3 Melting Point 80-82ºC(lit.)
MSDS Chinese USA Flash Point 136.8±17.2 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of coniferyl aldehyde


Coniferaldehyde (Ferulaldehyde), isolated from the ethanol extract of Vitex rotundifolia fruits, is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde exerts anti-inflammatory properties in response to LPS. Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells[1].

 Names

Name coniferyl aldehyde
Synonym More Synonyms

 coniferyl aldehyde Biological Activity

Description Coniferaldehyde (Ferulaldehyde), isolated from the ethanol extract of Vitex rotundifolia fruits, is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde exerts anti-inflammatory properties in response to LPS. Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells[1].
Related Catalog
References

[1]. Kim KM, et al. Coniferaldehyde inhibits LPS-induced apoptosis through the PKC α/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells. Environ Toxicol Pharmacol. 2016 Dec;48:85-93.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 338.8±27.0 °C at 760 mmHg
Melting Point 80-82ºC(lit.)
Molecular Formula C10H10O3
Molecular Weight 178.185
Flash Point 136.8±17.2 °C
Exact Mass 178.062988
PSA 46.53000
LogP 1.35
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.593
Storage condition 2-8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases 26-37/39
RIDADR NONH for all modes of transport
HS Code 2912499000

 Synthetic Route

 Customs

HS Code 2912499000
Summary 2912499000. other aldehyde-ethers, aldehyde-phenols and aldehydes with other oxygen function. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

 Articles8

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A derivatization and validation strategy for determining the spatial localization of endogenous amine metabolites in tissues using MALDI imaging mass spectrometry.

J. Mass Spectrom. 49(8) , 665-73, (2014)

Imaging mass spectrometry (IMS) studies increasingly focus on endogenous small molecular weight metabolites and consequently bring special analytical challenges. Since analytical tissue blanks do not ...

Reagent precoated targets for rapid in-tissue derivatization of the anti-tuberculosis drug isoniazid followed by MALDI imaging mass spectrometry.

J. Am. Soc. Mass Spectrom. 22(8) , 1409-19, (2011)

Isoniazid (INH) is an important component of front-line anti-tuberculosis therapy with good serum pharmacokinetics but unknown ability to penetrate tuberculous lesions. However, endogenous background ...

Antifungal synergistic effect of scopoletin, a hydroxycoumarin isolated from Melia azedarach L. fruits.

J. Agric. Food Chem. 53(8) , 2922-7, (2005)

In the continuous search for antifungal compounds from plants, the hydroxycoumarin scopoletin (1) was isolated from seed kernels of Melia azedarach L. from which three other compounds, vanillin (2), 4...

 Synonyms

Ferulaldehyde
(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enal
(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enal
Ferulyl aldehyde
2-Propenal, 3-(4-hydroxy-3-methoxyphenyl), (E)-
4-hydroxy-3-methoxy-benzaldehyde
MFCD00075811
4-hydroxy-3-methoxy-cinnamon-aldehyde
2-Propenal, 3-(4-hydroxy-3-methoxyphenyl)-, (2E)-
coniferaldehyde
4-hydroxy-3-methoxycinnamic aldehyde
EINECS 207-278-4
4-HYDROXY-3-METHOXYCINNAMALDEHYDE
(2E)-3-(4-Hydroxy-3-methoxyphenyl)acrylaldehyde
coniferyl aldehyde
Coniferylaldehyde
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