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458-36-6

458-36-6 structure
458-36-6 structure
  • Name: coniferyl aldehyde
  • Chemical Name: coniferyl aldehyde
  • CAS Number: 458-36-6
  • Molecular Formula: C10H10O3
  • Molecular Weight: 178.185
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2018-06-15 00:03:52
  • Modify Date: 2024-01-03 01:32:37
  • Coniferaldehyde (Ferulaldehyde), isolated from the ethanol extract of Vitex rotundifolia fruits, is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde exerts anti-inflammatory properties in response to LPS. Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells[1].

Name coniferyl aldehyde
Synonyms Ferulaldehyde
(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enal
(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enal
Ferulyl aldehyde
2-Propenal, 3-(4-hydroxy-3-methoxyphenyl), (E)-
4-hydroxy-3-methoxy-benzaldehyde
MFCD00075811
4-hydroxy-3-methoxy-cinnamon-aldehyde
2-Propenal, 3-(4-hydroxy-3-methoxyphenyl)-, (2E)-
coniferaldehyde
4-hydroxy-3-methoxycinnamic aldehyde
EINECS 207-278-4
4-HYDROXY-3-METHOXYCINNAMALDEHYDE
(2E)-3-(4-Hydroxy-3-methoxyphenyl)acrylaldehyde
coniferyl aldehyde
Coniferylaldehyde
Description Coniferaldehyde (Ferulaldehyde), isolated from the ethanol extract of Vitex rotundifolia fruits, is an effective inducer of heme oxygenase-1 (HO-1). Coniferaldehyde exerts anti-inflammatory properties in response to LPS. Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells[1].
Related Catalog
References

[1]. Kim KM, et al. Coniferaldehyde inhibits LPS-induced apoptosis through the PKC α/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells. Environ Toxicol Pharmacol. 2016 Dec;48:85-93.

Density 1.2±0.1 g/cm3
Boiling Point 338.8±27.0 °C at 760 mmHg
Melting Point 80-82ºC(lit.)
Molecular Formula C10H10O3
Molecular Weight 178.185
Flash Point 136.8±17.2 °C
Exact Mass 178.062988
PSA 46.53000
LogP 1.35
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.593
Storage condition 2-8°C
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases 26-37/39
RIDADR NONH for all modes of transport
HS Code 2912499000
HS Code 2912499000
Summary 2912499000. other aldehyde-ethers, aldehyde-phenols and aldehydes with other oxygen function. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%