N-3-Oxo-octanoyl-L-homoserine lactone
N-3-Oxo-octanoyl-L-homoserine lactone structure
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Common Name | N-3-Oxo-octanoyl-L-homoserine lactone | ||
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| CAS Number | 147795-39-9 | Molecular Weight | 241.28 | |
| Density | 1.12g/cm3 | Boiling Point | 490.1ºC at 760mmHg | |
| Molecular Formula | C12H19NO4 | Melting Point | 96-97 ºC (ethyl acetate ) | |
| MSDS | Chinese USA | Flash Point | 250.2ºC | |
Use of N-3-Oxo-octanoyl-L-homoserine lactoneN-3-Oxo-octanoyl-L-homoserine lactone, a quorum-sensing signal, is an Agrobacterium autoinducer[1][2]. |
| Name | 3-oxo-N-[(3S)-2-oxooxolan-3-yl]octanamide |
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| Synonym | More Synonyms |
| Description | N-3-Oxo-octanoyl-L-homoserine lactone, a quorum-sensing signal, is an Agrobacterium autoinducer[1][2]. |
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| Related Catalog | |
| In Vitro | N-3-Oxo-octanoyl-L-homoserine lactone (3OC8-HSL) pretreatment (10 μM; for 2 days) exerts strong inhibitory effect on pathogen proliferation in the leaves[1]. Plants treated with N-3-Oxo-octanoyl-L-homoserine lactone shows increased activities of defense-related enzymes including peroxidase, catalase, phenylalanine ammonialyase, and superoxide dismutase[1]. |
| References |
| Density | 1.12g/cm3 |
|---|---|
| Boiling Point | 490.1ºC at 760mmHg |
| Melting Point | 96-97 ºC (ethyl acetate ) |
| Molecular Formula | C12H19NO4 |
| Molecular Weight | 241.28 |
| Flash Point | 250.2ºC |
| Exact Mass | 241.131409 |
| PSA | 72.47000 |
| LogP | 1.73860 |
| Appearance of Characters | White solid Chemodex |
| Vapour Pressure | 9.41E-10mmHg at 25°C |
| Index of Refraction | 1.484 |
| Storage condition | -20°C |
| Water Solubility | Slightly soluble (7.2 g/L) (25 ºC) |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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Medicinal chemistry as a conduit for the modulation of quorum sensing.
J. Med. Chem. 53 , 7467-89, (2010)
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Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators.
Bioorg. Med. Chem. Lett. 18 , 5978-81, (2008) A focused library of N-aryl l-homoserine lactones was designed around known lactone leads and evaluated for antagonistic and agonistic activity against quorum-sensing receptors in Agrobacterium tumefa... |
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Synthetic ligands that activate and inhibit a quorum-sensing regulator in Pseudomonas aeruginosa.
Bioorg. Med. Chem. Lett. 18 , 3072-5, (2008) The transcription factor QscR is a regulator of quorum sensing in Pseudomonas aeruginosa and plays a role in controlling virulence in this prevalent opportunistic pathogen. This study outlines the dis... |
| Aai-OOHL |
| LAE |
| HSL-OOA |
| OOHL |
| N-(3-Oxooctanoyl)-L-homoserine lactone |
| 3-Oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]octanamide |
| 3-Oxo-N-[(3S)-2-oxotetrahydro-3-furanyl]octanamide |
| Octanamide, 3-oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]- |
| 3-OXO-OCTANOIC ACID (2-OXO-TETRAHYDRO-FURAN-3-YL)-AMIDE |