Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

SPQ

SPQ is being used to examine and measure membrane chloride transport mechanisms.

  • CAS Number: 83907-40-8
  • MF: C13H15NO4S
  • MW: 281.32800
  • Catalog: Biochemical Assay Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 299ºC dec.
  • Flash Point: N/A

Myrtenal

Myrtenal ((±)-Myrtenal) is a monoterpene that acts as an antineoplastic agent. Myrtenal inhibits liver cancer by preventing DEN-PB-induced upregulation of TNF-α protein expression.

  • CAS Number: 564-94-3
  • MF: C10H14O
  • MW: 150.22
  • Catalog: Cancer
  • Density: 1.061g/cm3
  • Boiling Point: 215.7ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 78.9ºC

1,5-Dibromopentane-d4

1,5-Dibromopentane-d4 is the deuterium labeled 1,5-Dibromopentane[1].

  • CAS Number: 1219803-90-3
  • MF: C5H6D4Br2
  • MW: 233.965
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 224.5±8.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 94.7±17.7 °C

WAY-604440

WAY-604440 is an active molecule.

  • CAS Number: 501113-03-7
  • MF: C16H13ClN4OS
  • MW: 344.82
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 597.0±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 314.9±32.9 °C

Transfluthrin

Transfluthrin is a fast-acting pyrethroid insecticide and mosquito repellent. Transfluthrin is against flying insects, such as mosquito and flies, and in agriculture material pests[1][2].

  • CAS Number: 118712-89-3
  • MF: C15H12Cl2F4O2
  • MW: 371.154
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 351.4±42.0 °C at 760 mmHg
  • Melting Point: 32ºC
  • Flash Point: 115.5±17.0 °C

2-Ethoxybenzamide

2-Ethoxybenzamide is widely used as an antipyretic anodyne.

  • CAS Number: 938-73-8
  • MF: C9H11NO2
  • MW: 165.189
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 302.0±25.0 °C at 760 mmHg
  • Melting Point: 129-134 °C
  • Flash Point: 153.7±19.5 °C

EDMPC

EDMPC, a cationic lipid, has an enhanced ability to deliver DNA to pulmonary tissues. EDMPC mediates intralobar DNA delivery to rodents[1].

  • CAS Number: 183283-19-4
  • MF: C38H77NO8P+
  • MW: 706.99
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sagittatoside B

Sagittatoside B is a natural compound isolated from traditional Chinese herb Yinyanghuo (Herba Epimdii).

  • CAS Number: 118525-36-3
  • MF: C32H38O14
  • MW: 646.636
  • Catalog: Others
  • Density: 1.53
  • Boiling Point: 895.5±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 286.5±27.8 °C

MeOSuc-Ala-Ala-Pro-Val-pNA

MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive fluorogenic substrate of human leukocyte and porcine pancreatic elastase[1].

  • CAS Number: 70967-90-7
  • MF: C27H38N6O9
  • MW: 590.62500
  • Catalog: Others
  • Density: 1.297g/cm3
  • Boiling Point: 908.4ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 503.2ºC

Stick Insect Hypertrehalosaemic Factor II

Stick Insect Hypertrehalosaemic Factor II is a synthetic peptide. Stick Insect Hypertrehalosaemic Factor II has the same FAB spectra, reversed-phase high-performance liquid chromatographic behavior, and biological behavior as the natural material. Stick Insect Hypertrehalosaemic Factor II can be used for the research of hypertrehalosaemic effect[1].

  • CAS Number: 102067-93-6
  • MF: C54H75N13O15
  • MW: 1146.25
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Lobelanine

Lobelanine (8,10-Diphenyllobelidione) is a chemical precursor for the biosynthesis of Lobeline. Lobeline is a partial nicotinic agonist and is used as a smoking cessation agent[1][2].

  • CAS Number: 579-21-5
  • MF: C22H25NO2
  • MW: 335.43900
  • Catalog: Others
  • Density: 1.076g/cm3
  • Boiling Point: 476.4ºC at 760mmHg
  • Melting Point: 99°
  • Flash Point: 196.2ºC

Fmoc-D-2-Nal-OH

Fmoc-D-2-Nal-OH is an alanine derivative[1].

  • CAS Number: 138774-94-4
  • MF: C28H23NO4
  • MW: 437.487
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 690.7±50.0 °C at 760 mmHg
  • Melting Point: 191 °C
  • Flash Point: 371.6±30.1 °C

1,2,3,6-Tetrahydro-2,3'-bipyridine

(R,S)-Anatabine is a a minor tobacco alkaloid found in the Solanaceae family of plants that can be used as a specific marker for the detection of tobacco use[1].

  • CAS Number: 2743-90-0
  • MF: C10H12N2
  • MW: 160.216
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 269.0±28.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 116.5±24.0 °C

Bilirubin conjugate

Bilirubin Conjugate disodium is a ditaurate derivative of Bilirubin. Bilirubin, a major end product of heme breakdown, is an important constituent of bile[1].

  • CAS Number: 68683-34-1
  • MF: C37H44N6Na2O10S2
  • MW: 842.88900
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(1S,3R,6S,8R,9S,10E,12S,14S)-6,9,14-Tris(acetyloxy)-3,12-dihydroxy-1,5,16,16-tetramethyltricyclo[9.3.1.14,8]hexadeca-4,10-dien-2-one

Taxuspine W is a natural product, that can be isolated from the Japanese Yew Taxus cuspidata[1].

  • CAS Number: 181309-92-2
  • MF: C26H36O9
  • MW: 492.56
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 605.1±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 195.1±25.0 °C

Importazole

Importazole is a small molecule inhibitor of the nuclear transport receptor importin-β.

  • CAS Number: 662163-81-7
  • MF: C20H22N4
  • MW: 318.415
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 516.8±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 266.3±27.9 °C

Bavituximab

Bavituximab (Anti-Human Phosphatidylserine Recombinant Antibody) is a phosphatidylserine (PS)-targeting monoclonal antibody, suppresses tumor growth by targeting tumor vasculature and reactivating antitumor immunity. Bavituximab plus Paclitaxel (HY-B0015) and Carboplatin (HY-17393), have enhanced inhibition on non-small-cell lung cancer[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ICG-carboxylic acid

ICG-carboxylic acid is near-infrared (NIR) fluorescent probe. ICG is a fluorescent dye used in medical diagnostics. ICG has absorption peaking at 800 nm and can absorb the near IR laser energy and release heat in the dyed tissue[1][2].

  • CAS Number: 181934-09-8
  • MF: C45H50N2O5S
  • MW: 730.95
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

8-C-Glucosyl-(R)-aloesol

8-C-Glucosyl-(R)-aloesol ((R)-Aloesinol) is a bioactive chromone analogue[1].

  • CAS Number: 135097-55-1
  • MF: C19H24O9
  • MW: 396.39
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

EGTA

EGTA is a specific calcium ion chelator. EGTA has an apparent calcium dissociation constant (Kd) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca2+ over Mg2+ (Mg2+ Kd 1-10 mM). EGTA significantly inhibited the substrate adherence capacity of inflammatory macrophages[1][2].

  • CAS Number: 67-42-5
  • MF: C14H24N2O10
  • MW: 380.348
  • Catalog: Inflammation/Immunology
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 678.0±55.0 °C at 760 mmHg
  • Melting Point: 241 °C (dec.)(lit.)
  • Flash Point: 363.9±31.5 °C

Veratramide

3,4-Dimethoxybenzamide, amide, is isolated from the solid culture of Streptoverticillium morookaense. 3,4-Dimethoxybenzamide can be used as the starting material to preparation Itopride hydrochloride[1][2].

  • CAS Number: 1521-41-1
  • MF: C9H11NO3
  • MW: 181.189
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 278.4±25.0 °C at 760 mmHg
  • Melting Point: 163-164℃
  • Flash Point: 126.1±19.5 °C

Angulatin B

Angulatin B is a natural product that can be found in the root bark of Celastrus angulatus[1].

  • CAS Number: 142546-07-4
  • MF: C34H46O15
  • MW: 694.72
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Rodorubicin

Rodorubicin (Cytorhodin S) is a tetraglycosidic anthracycline with preclinical antitumor activity[1].

  • CAS Number: 96497-67-5
  • MF: C48H64N2O17
  • MW: 941.025
  • Catalog: Cancer
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Salviaflaside

Salviaflaside is a main bioactive component of Spica Prunellae[1].

  • CAS Number: 178895-25-5
  • MF: C24H26O13
  • MW: 522.45500
  • Catalog: Others
  • Density: 1.625g/cm3
  • Boiling Point: 873.2ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 296.6ºC

6,7,8-Trihydroxy-2-(2-Phenethyl) chromone

6,7,8-Trihydroxy-2-(2-Phenethyl) chromone is a chromone derivative with anti-inflammatory effects[1].

  • CAS Number: 2803559-82-0
  • MF: C17H18O5
  • MW: 302.32
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PNPG

PNPG(4-Nitrophenyl-β-D- glucopyranoside) is a chromogenic β-D-glucosidase substrate, producing a yellow solution upon cleavage.

  • CAS Number: 2492-87-7
  • MF: C12H15NO8
  • MW: 301.249
  • Catalog: Biochemical Assay Reagents
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 582.2±50.0 °C at 760 mmHg
  • Melting Point: 165-168 °C
  • Flash Point: 305.9±30.1 °C

Boc-O-(2-bromo-Cbz)-D-tyrosine

Boc-D-Tyr(2-Br-Z)-OH is a tyrosine derivative[1].

  • CAS Number: 81189-61-9
  • MF: C22H24BrNO7
  • MW: 494.332
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 634.9±55.0 °C at 760 mmHg
  • Melting Point: 90-95°C (lit.)
  • Flash Point: 337.8±31.5 °C

Sibrotuzumab

Sibrotuzumab (BIBH 1) is a humanized IgG1 monoclonal antibody targets fibroblast activation protein (FAP). Sibrotuzumab can be used for the research of colorectal cancer and non-small cell lung cancer (NSCLC)[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SV40 T-Ag-derived NLS peptide

SV40 T-Ag-derived NLS peptide is a nuclear localization signal DNA tagged to this peptide efficiently translocates into the cell nucleus[1].

  • CAS Number: 105425-98-7
  • MF: C66H111N19O18S
  • MW: 1490.77000
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Orientin

Orientin is a naturally occurring bioactive flavonoid that possesses diverse biological properties, including anti-inflammation, anti-oxidative, anti-tumor, and cardio protection. Orientin is a promising neuroprotective agent suitable for therapy for neuropathic pain[1][2].

  • CAS Number: 28608-75-5
  • MF: C21H20O11
  • MW: 448.377
  • Catalog: Cancer
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 816.1±65.0 °C at 760 mmHg
  • Melting Point: 260-285ºC
  • Flash Point: 289.1±27.8 °C