Lobelanine

Modify Date: 2024-01-02 14:23:54

Lobelanine Structure
Lobelanine structure
Common Name Lobelanine
CAS Number 579-21-5 Molecular Weight 335.43900
Density 1.076g/cm3 Boiling Point 476.4ºC at 760mmHg
Molecular Formula C22H25NO2 Melting Point 99°
MSDS N/A Flash Point 196.2ºC

 Use of Lobelanine


Lobelanine (8,10-Diphenyllobelidione) is a chemical precursor for the biosynthesis of Lobeline. Lobeline is a partial nicotinic agonist and is used as a smoking cessation agent[1][2].

 Names

Name 2-[(2R,6S)-1-methyl-6-phenacylpiperidin-2-yl]-1-phenylethanone
Synonym More Synonyms

 Lobelanine Biological Activity

Description Lobelanine (8,10-Diphenyllobelidione) is a chemical precursor for the biosynthesis of Lobeline. Lobeline is a partial nicotinic agonist and is used as a smoking cessation agent[1][2].
Related Catalog
References

[1]. Guangrong Zheng, Peter A. Crooks. (2015) ChemInform Abstract: Synthesis of Lobeline, Lobelane and Their Analogues. A Review. ChemInform 46:42, pages no-no.

[2]. Stead LF, et al. Lobeline for smoking cessation. Cochrane Database Syst Rev. 2012;2012(2):CD000124. Published 2012 Feb 15.

 Chemical & Physical Properties

Density 1.076g/cm3
Boiling Point 476.4ºC at 760mmHg
Melting Point 99°
Molecular Formula C22H25NO2
Molecular Weight 335.43900
Flash Point 196.2ºC
Exact Mass 335.18900
PSA 37.38000
LogP 4.32320
Index of Refraction 1.554
Storage condition 2-8°C

 Safety Information

RIDADR UN 1544
Packaging Group III
Hazard Class 6.1(b)

 Synonyms

Lobelanine
1-Methyl-2r,6c-diphenacyl-piperidin
cis-2,2'-(1-methyl-2,6-piperidinediyl)bis[1-phenyl-ethanone]
1-methyl-2r,6c-diphenacyl-piperidine
Ethanone,2,2'-(1-methyl-2,6-piperidinediyl)bis(1-phenyl-,cis
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