Lobelanine

Names

[ CAS No. ]:
579-21-5

[ Name ]:
Lobelanine

[Synonym ]:
Lobelanine
1-Methyl-2r,6c-diphenacyl-piperidin
cis-2,2'-(1-methyl-2,6-piperidinediyl)bis[1-phenyl-ethanone]
1-methyl-2r,6c-diphenacyl-piperidine
Ethanone,2,2'-(1-methyl-2,6-piperidinediyl)bis(1-phenyl-,cis

Biological Activity

[Description]:

Lobelanine (8,10-Diphenyllobelidione) is a chemical precursor for the biosynthesis of Lobeline. Lobeline is a partial nicotinic agonist and is used as a smoking cessation agent[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Guangrong Zheng, Peter A. Crooks. (2015) ChemInform Abstract: Synthesis of Lobeline, Lobelane and Their Analogues. A Review. ChemInform 46:42, pages no-no.

[2]. Stead LF, et al. Lobeline for smoking cessation. Cochrane Database Syst Rev. 2012;2012(2):CD000124. Published 2012 Feb 15.

Chemical & Physical Properties

[ Density]:
1.076g/cm3

[ Boiling Point ]:
476.4ºC at 760mmHg

[ Melting Point ]:
99°

[ Molecular Formula ]:
C₂₂H₂₅NO₂

[ Molecular Weight ]:
335.43900

[ Flash Point ]:
196.2ºC

[ Exact Mass ]:
335.18900

[ PSA ]:
37.38000

[ LogP ]:
4.32320

[ Index of Refraction ]:
1.554

[ Storage condition ]:
2-8°C

Safety Information

[ RIDADR ]:
UN 1544

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

Precursor & DownStream

Precursor

DownStream

Related Compounds

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