Benzyl-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
MS-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Thalidomide D4 is a deuterium labeled Thalidomide. Thalidomide is initially promoted as a sedative, inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ~250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties[1][2].
Propargyl-PEG10-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Boc-N-Amido-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
m-PEG6-Hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Pomalidomide-amino-PEG5-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Biotin-PEG4-alkyne is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Trityl-PEG10-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Benzyl-PEG5-NHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Boc-NH-PEG7-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Pomalidomide-CO-C5-azide (Compound PA) is a ligand for E3 ligase bearing a bioorthogonal group azide. Pomalidomide-CO-C5-azide can be used to synthesize PROTACs with anticancer activity[1].
5-endo-BCN-pentanoic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Mal-amido-PEG9-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTAC α-synuclein degrader 3 (compound 5) is a potent and selective PROTAC α-synuclein degrader. PROTAC α-synuclein degrader 3 can be used in research of Parkinson's disease[1].
Methoxy-Tr-NH-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Mal-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
APN-NH2 is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Amino-PEG4-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTAC Linker 16 is a polyethylene glycol (PEG)-based PROTAC linker. PROTAC Linker 16 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Bromo-PEG6-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Ald-Ph-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Fmoc-Gly-NH-CH2-O-CH2-Cbz is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Gly-NH-CH2-O-CH2-Cbz can be used in the synthesis of the Deruxtecan[1].
m-PEG5-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Azido-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Boc-6-aminohexanoic acid is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
N-(Azido-PEG2)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
THP-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PEG3-bis(phosphonic acid diethyl ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].