Ms-PEG6-THP

Modify Date: 2024-01-31 12:05:29

Ms-PEG6-THP Structure
Ms-PEG6-THP structure
Common Name Ms-PEG6-THP
CAS Number 42607-89-6 Molecular Weight 444.54
Density N/A Boiling Point N/A
Molecular Formula C18H36O10S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ms-PEG6-THP


Ms-PEG6-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Ms-PEG6-THP

 Ms-PEG6-THP Biological Activity

Description Ms-PEG6-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C18H36O10S
Molecular Weight 444.54