MS-PEG1-THP

Modify Date: 2024-01-09 16:23:54

MS-PEG1-THP Structure
MS-PEG1-THP structure
Common Name MS-PEG1-THP
CAS Number 1309248-13-2 Molecular Weight 224.27
Density N/A Boiling Point N/A
Molecular Formula C8H16O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MS-PEG1-THP


MS-PEG1-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name MS-PEG1-THP

 MS-PEG1-THP Biological Activity

Description MS-PEG1-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C8H16O5S
Molecular Weight 224.27