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119096-95-6

119096-95-6 structure
119096-95-6 structure
  • Name: Propargyl-PEG1-THP
  • Chemical Name: Propargyl-PEG1-THP
  • CAS Number: 119096-95-6
  • Molecular Formula: C10H16O3
  • Molecular Weight: 184.23
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-06-19 18:04:20
  • Modify Date: 2024-01-09 20:46:36
  • Propargyl-PEG1-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Propargyl-PEG1-THP
Description Propargyl-PEG1-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C10H16O3
Molecular Weight 184.23