17598-96-8

17598-96-8 structure

17598-96-8 structure

Name: HO-PEG13-OH
Chemical Name: 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
CAS Number: 17598-96-8
Molecular Formula: C₂₆H₅₄O₁₄
Molecular Weight: 590.69900
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2016-08-08 08:05:09
Modify Date: 2024-01-09 17:58:19
HO-PEG13-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Synonyms	3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaoctatriacontane-1,38-diol tridecaethylene glycol EINECS 241-569-7

Description	HO-PEG13-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density	1.116g/cm3
Boiling Point	631.6ºC at 760mmHg
Molecular Formula	C₂₆H₅₄O₁₄
Molecular Weight	590.69900
Exact Mass	590.35100
PSA	151.22000
Vapour Pressure	1.32E-18mmHg at 25°C
Index of Refraction	1.465

HS Code	2909499000

361543-06-8 structure

361543-06-8

~77%

17598-96-8 structure

17598-96-8

Literature: Andrus, Merritt B.; Turner, Timothy M.; Updegraff, Emily P.; Sauna, Zuben E.; Ambudkar, Suresh V. Tetrahedron Letters, 2001 , vol. 42, # 23 p. 3819 - 3822

41024-91-3 structure

41024-91-3

~%

17598-96-8 structure

17598-96-8

Literature: Jayasuriya, Nimal; Bosak, Stanislav; Regen, Steven L. Journal of the American Chemical Society, 1990 , vol. 112, # 15 p. 5851 - 5854

128660-97-9 structure

128660-97-9

~%

17598-96-8 structure

17598-96-8

Literature: Jayasuriya, Nimal; Bosak, Stanislav; Regen, Steven L. Journal of the American Chemical Society, 1990 , vol. 112, # 15 p. 5851 - 5854

4792-15-8 structure

4792-15-8

~%

17598-96-8 structure

17598-96-8

Literature: Andrus, Merritt B.; Turner, Timothy M.; Updegraff, Emily P.; Sauna, Zuben E.; Ambudkar, Suresh V. Tetrahedron Letters, 2001 , vol. 42, # 23 p. 3819 - 3822

57671-28-0 structure

57671-28-0

~%

17598-96-8 structure

17598-96-8

Literature: Andrus, Merritt B.; Turner, Timothy M.; Updegraff, Emily P.; Sauna, Zuben E.; Ambudkar, Suresh V. Tetrahedron Letters, 2001 , vol. 42, # 23 p. 3819 - 3822

80322-82-3 structure

80322-82-3

~%

17598-96-8 structure

17598-96-8

Literature: Andrus, Merritt B.; Turner, Timothy M.; Updegraff, Emily P.; Sauna, Zuben E.; Ambudkar, Suresh V. Tetrahedron Letters, 2001 , vol. 42, # 23 p. 3819 - 3822

112-27-6 structure

112-27-6

~%

17598-96-8 structure

17598-96-8

Literature: Andrus, Merritt B.; Turner, Timothy M.; Updegraff, Emily P.; Sauna, Zuben E.; Ambudkar, Suresh V. Tetrahedron Letters, 2001 , vol. 42, # 23 p. 3819 - 3822

HS Code	2909499000
Summary	2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%