- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Pentaethylene glycol di(p-toluenesulfonate)
- Price: ￥768.0/5g ￥268.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Liu jia
41024-91-3
41024-91-3 structure
- Name: Pentaethylene glycol di(p-toluenesulfonate)
- Chemical Name: penta(ethylene glycol) di-p-toluenesulfonate
- CAS Number: 41024-91-3
- Molecular Formula: C24H34O10S2
- Molecular Weight: 546.65100
- Catalog: Chemical reagent Organic reagent Tosylate
- Create Date: 2018-05-07 08:00:00
- Modify Date: 2024-01-03 01:09:14
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Pentaethylene glycol di(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | penta(ethylene glycol) di-p-toluenesulfonate |
|---|---|
| Synonyms |
Pentaethylene glycol di-p-toluenesulfonate
2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate MFCD00012204 |
| Description | Pentaethylene glycol di(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.26 |
|---|---|
| Boiling Point | 661.4ºC at 760mmHg |
| Molecular Formula | C24H34O10S2 |
| Molecular Weight | 546.65100 |
| Flash Point | 353.8ºC |
| Exact Mass | 546.15900 |
| PSA | 140.42000 |
| LogP | 4.64220 |
| Index of Refraction | n20/D 1.524(lit.) |
| Water Solubility | Not miscible or difficult to mix in water. |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | 36/37/38 |
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2909499000 |
|
~10%
41024-91-3 |
| Literature: Bouzide, Abderrahim; Sauve, Gilles Organic Letters, 2002 , vol. 4, # 14 p. 2329 - 2332 |
|
~99%
41024-91-3 |
| Literature: Bonger, Kimberly M.; van den Berg, Richard J.B.H.N.; Heitman, Laura H.; IJzerman, Ad P.; Oosterom, Julia; Timmers, Cornelis M.; Overkleeft, Herman S.; van der Marel, Gijsbert A. Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 14 p. 4841 - 4856 |
|
~%
41024-91-3 |
| Literature: Fenton, David E.; Parkin, Donald; Newton, Roger F. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 449 - 454 |
| HS Code | 2909499000 |
|---|---|
| Summary | 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |