128660-97-9
128660-97-9 structure
- Name: THP-PEG4-OH
- Chemical Name: 2-(2-{2-[2-(Tetrahydro-2H-pyran-2-yloxy)ethoxy]ethoxy}ethoxy)ethanol
- CAS Number: 128660-97-9
- Molecular Formula: C13H26O6
- Molecular Weight: 278.342
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-25 07:54:59
- Modify Date: 2024-01-02 23:48:22
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THP-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-(2-{2-[2-(Tetrahydro-2H-pyran-2-yloxy)ethoxy]ethoxy}ethoxy)ethanol |
|---|---|
| Synonyms |
Ethanol, 2-[2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]ethoxy]-
2-(2-{2-[2-(Tetrahydro-2H-pyran-2-yloxy)ethoxy]ethoxy}ethoxy)ethanol |
| Description | THP-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 394.0±42.0 °C at 760 mmHg |
| Molecular Formula | C13H26O6 |
| Molecular Weight | 278.342 |
| Flash Point | 192.1±27.9 °C |
| Exact Mass | 278.172943 |
| LogP | -1.46 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.467 |