Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Acetyl Pentapeptide-1

Acetyl pentapeptide-1 是一种五肽。Acetyl pentapeptide-1 与其他寡肽结合可增强皮肤屏障功能。

  • CAS Number: 97530-32-0
  • MF: C32H51N9O10
  • MW: 721.802
  • Catalog: Metabolic Disease
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Medicagol

Medicagol, is a natural compound isolated from Medicago sativa[1].

  • CAS Number: 1983-72-8
  • MF: C16H8O6
  • MW: 296.23100
  • Catalog: Others
  • Density: 1.644g/cm3
  • Boiling Point: 552.6ºC at 760mmHg
  • Melting Point: >300℃
  • Flash Point: 288ºC

GenBank AAF44751

GenBank AAF44751 is a synthetic peptide, can be used for the research of biology studies.

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bruceantinol A

Bruceantinol A, a natural compound, can be isolated from Brucea javanica seeds[1].

  • CAS Number: 948038-36-6
  • MF: C29H36O13
  • MW: 592.588
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 839.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 274.1±27.8 °C

LyP-1

LyP-1 is a cyclic 9‐amino‐acids tumor homing peptide and selectively bind to p32 receptors overexpressed in various tumor-associated cells[1].

  • CAS Number: 454487-07-1
  • MF: C36H65N17O12S2
  • MW: 992.14
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PENITREM A

Penitrem A is an indole diterpene neurotoxic alkaloid produced by Penicillium, acts as a selective BK channel antagonist with antiproliferative and anti-invasive activities against multiple malignancies. Penitrem A increases the spontaneous release of endogenous glutamate, gamma-aminobutyric acid (GABA) and aspartate from cerebrocortical synaptosomes, and induces tremorgenic syndromes in animals[1][2].

  • CAS Number: 12627-35-9
  • MF: C37H44ClNO6
  • MW: 634.201
  • Catalog: Cancer
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-Methoxyneochamaejasmine A

7-Methoxyneochamaejasmine A (compound 4) is a compound that can be found in Stellera chamaejasme L[1].

  • CAS Number: 402828-38-0
  • MF: C31H24O10
  • MW: 556.52
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 906.6±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 302.8±27.8 °C

OU749

OU749 is a potent γ-glutamyl transpeptidase (GGT) inhibitor with a Ki value of 17.6 µM. OU749 shows cytotoxicity[1].

  • CAS Number: 519170-13-9
  • MF: C16H15N3O3S2
  • MW: 361.44
  • Catalog: Cancer
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 565.6±52.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 295.9±30.7 °C

Cimigenol

Cimigenol is an active compound isolated from Cimicifuga, with potent anti-tumor activity[1].

  • CAS Number: 3779-59-7
  • MF: C30H48O5
  • MW: 488.69900
  • Catalog: Cancer
  • Density: 1.22g/cm3
  • Boiling Point: 610.6ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 323.1ºC

2',4',5,7-Tetrahydroxyisoflavone

2′-Hydroxygenistein is a natural product that can be isolated from Crotalaria pallida and C. assamica. 2′-Hydroxygenistein shows anti-inflammatory activity. 2′-Hydroxygenistein shows significant concentration-dependent inhibitory effects on the release of β-glucuronidase and lysozyme from rat neutrophils, with IC50 values of 5.9 ± 1.4 and 9.7 ± 3.5 μM, respectively[1].

  • CAS Number: 1156-78-1
  • MF: C15H10O6
  • MW: 286.24
  • Catalog: Inflammation/Immunology
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 619.1±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 240.7±25.0 °C

2-(Trimethylammonio)ethyl dodecyl phosphate

Dodecylphosphocholine is a detergent widely utilized in NMR studies of membrane proteins[1][2].

  • CAS Number: 29557-51-5
  • MF: C17H38NO4P
  • MW: 351.462
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

COH34 analog 1

COH34 analog 1, a metabolite, is an oxidized analog of COH34. COH34 is a potent poly(ADP-ribose) glycohydrolase (PARG) inhibitor[1].

  • CAS Number: 314248-24-3
  • MF: C18H15NO3S
  • MW: 325.38
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Napropamide

Napropamide is a selective systemic amide herbicide used to control a number of annual grasses and broad-leaved weeds.

  • CAS Number: 15299-99-7
  • MF: C17H21NO2
  • MW: 271.354
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 430.2±28.0 °C at 760 mmHg
  • Melting Point: 73-78 °C(lit.)
  • Flash Point: 214.0±24.0 °C

5(S)​-​HPETE

5(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 5-LO on arachidonic acid. 5(S)-HpETE is metabolized to leukotriene A4 (LTA4), a key intermediate in the formation of LTs.

  • CAS Number: 71774-08-8
  • MF: C20H32O4
  • MW: 336.466
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 518.0±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 175.6±23.6 °C

Tetradecyltrimethylammonium-d29 bromide

Tetradecyltrimethylammonium-d29 (bromide) is the deuterium labeled Tetradecyltrimethylammonium (bromide)[1]. Tetradecyltrimethylammonium bromide, an organic building block, is a cationic surfactant with asymmetrical structure[2][3].

  • CAS Number: 95523-73-2
  • MF: C17H9BrD29N
  • MW: 365.57300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Butenoyl coenzyme A lithium

2-Butenoyl coenzyme A (lithium), an active compound, can be used as a substrate for plasmodium falciparum enyl-ACP reductases and other enyl-CoA reductases. 2-Butenoyl coenzyme A lithium can be used as a substrate analogue to study the kinetics of β-hydroxyacyl-acyl-carrier protein (ACP) dehydratase (FabZ)[1].

  • CAS Number: 102680-35-3
  • MF: C25H40N7O17P3S
  • MW: 835.60800
  • Catalog: Others
  • Density: 1.82g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(Rac)-16:0PI(3,5)P2-d5 ammonium

(Rac)-16:0PI(3,5)P2-d5 (ammonium) is deuterium labeled (Rac)-16:0PI(3,5)P2 (ammonium).

  • CAS Number: 2260669-78-9
  • MF: C41H85D5N3O19P3
  • MW: 1027.11
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tetanus toxin 830-843

Tetanus toxin (830-843) a powerful neurotoxin that reaches by retroaxonal transport and transcytosis the cytoplasm ofspinal inhibitory intemeurons and blocks their ability to release neurotransmitters[1].

  • CAS Number: 119260-99-0
  • MF: C74H118N18O22
  • MW: 1611.84
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

NSI-189

NSI-189 is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine.IC50 value:Target: in vitro: NSI-189 has been shown to stimulate neurogenesis of human hippocampus-derived neural stem cells in vitro and in vivo. The hippocampus is responsible for the consolidation of information from short-term memory to long-term memory, along with spatial navigation [1] [2].in vivo: NSI-189 has been shown to increase the hippocampal volume of healthy adult mice by 20% [3].

  • CAS Number: 1270138-40-3
  • MF: C22H30N4O
  • MW: 366.500
  • Catalog: Neurological Disease
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 534.7±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 277.2±30.1 °C

Protopanaxatriol

20(R)-Protopanaxatriol is a natural aglycone of ginsenosides Re, Rf, Rg1, Rg2 and Rh.

  • CAS Number: 1453-93-6
  • MF: C30H52O4
  • MW: 476.732
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 590.0±50.0 °C at 760 mmHg
  • Melting Point: 261-263 °C
  • Flash Point: 240.1±24.7 °C

AA 147

AA147, a small molecule endoplasmic reticulum (ER) proteostasis regulator, selectively activates ATF6 arm of the unfolded protein response (UPR) extracted from patent WO2017117430A1, compound 147*[1].

  • CAS Number: 393121-74-9
  • MF: C16H17NO2
  • MW: 255.31
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tropatepine

Tropatepine is an anticholinergic muscarinic antagonist and can be used as an antiparkinsonian agent[1]. Tropatepine is used to combat against extrapyramidal syndrome induced by neuroleptic drugs[2].

  • CAS Number: 27574-24-9
  • MF: C22H23NS
  • MW: 333.49000
  • Catalog: Neurological Disease
  • Density: 1.19g/cm3
  • Boiling Point: 493.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 252ºC

JF549 TFA

JF549 TFA is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm[1].

  • CAS Number: 2245946-45-4
  • MF: C29H23F3N2O7
  • MW: 568.50
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hexapeptide-42

Hexapeptide-42 is a bioactive peptide and has been reported used as a cosmetic ingredient[1].

  • CAS Number: 197771-66-7
  • MF: C25H46N10O8S
  • MW: 646.76
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Antioxidant agent-14

Antioxidant agent-14 is a kaempferol glycoside isolated from the leaves of Brassica juncea[1].

  • CAS Number: 1203589-26-7
  • MF: C39H50O26
  • MW: 934.80
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isotheaflavin

Isotheaflavin is one of antioxidant polyphenols in black tea[1].

  • CAS Number: 31701-93-6
  • MF: C29H24O12
  • MW: 564.49400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Quercetin 3-O-robinobioside

Quercetin 3-O-robinobioside can be isolated from the leaves of Strychnos variabilis[1].

  • CAS Number: 52525-35-6
  • MF: C27H30O16
  • MW: 610.518
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 983.1±65.0 °C at 760 mmHg
  • Melting Point: 193-200℃
  • Flash Point: 325.4±27.8 °C

Dromostanolone propionate

Dromostanolone propionate (Drostanolone propionate) is a compound has antitumor activity against breast carcinoma[1]. Dromostanolone propionate inhibits the uptake of oestradiol-17ß by the tumour but has no apparent effect on the uptake by normal breast tissue [2]. Dromostanolone propionate implant pellet produces weight gains in animals and suppresses estrus in female animals[3].

  • CAS Number: 521-12-0
  • MF: C23H36O3
  • MW: 360.530
  • Catalog: Cancer
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 445.9±45.0 °C at 760 mmHg
  • Melting Point: 114-120ºC
  • Flash Point: 190.5±28.8 °C

epi-Nortrachelogenin

Epinortrachelogenin ((-)-Epinortrachelogenin) is a natural lignan found in the plateau medicinal plant Daphne acutiloba Rehd[1].

  • CAS Number: 125072-69-7
  • MF: C20H22O7
  • MW: 374.384
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 609.2±50.0 °C at 760 mmHg
  • Melting Point: 170-172℃
  • Flash Point: 217.3±23.6 °C

Biotinyl-Obestatin (rat) trifluoroacetate salt

Biotinyl-Obestatin, rat is a polypeptide.

  • CAS Number: 1815618-11-1
  • MF: C124H188N36O33S
  • MW: 2743.106
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A