Tropatepine

Modify Date: 2025-08-25 07:51:11

Tropatepine structure	Common Name	Tropatepine
	CAS Number	27574-24-9	Molecular Weight	333.49000
	Density	1.19g/cm3	Boiling Point	493.1ºC at 760mmHg
	Molecular Formula	C₂₂H₂₃NS	Melting Point	N/A
	MSDS	N/A	Flash Point	252ºC

Use of Tropatepine

Tropatepine is an anticholinergic muscarinic antagonist and can be used as an antiparkinsonian agent[1]. Tropatepine is used to combat against extrapyramidal syndrome induced by neuroleptic drugs[2].

Name	Tropatepine
Synonym	More Synonyms

Description	Tropatepine is an anticholinergic muscarinic antagonist and can be used as an antiparkinsonian agent[1]. Tropatepine is used to combat against extrapyramidal syndrome induced by neuroleptic drugs[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. P Celsis, et al. Effect of tropatepine, an anticholinergic drug, on regional cerebral blood flow in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry. 1989 Jul;52(7):917-8. [2]. P Arnoux, et al. Simultaneous determination of tropatepine and its major metabolites by high-performance liquid chromatographic-mass spectrometric identification. Application to metabolic and kinetic studies. J Chromatogr. 1986 Aug 22;381(1):75-82.

Description

Tropatepine is an anticholinergic muscarinic antagonist and can be used as an antiparkinsonian agent[1]. Tropatepine is used to combat against extrapyramidal syndrome induced by neuroleptic drugs[2].

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

References

[1]. P Celsis, et al. Effect of tropatepine, an anticholinergic drug, on regional cerebral blood flow in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry. 1989 Jul;52(7):917-8.

[2]. P Arnoux, et al. Simultaneous determination of tropatepine and its major metabolites by high-performance liquid chromatographic-mass spectrometric identification. Application to metabolic and kinetic studies. J Chromatogr. 1986 Aug 22;381(1):75-82.

Density	1.19g/cm3
Boiling Point	493.1ºC at 760mmHg
Molecular Formula	C₂₂H₂₃NS
Molecular Weight	333.49000
Flash Point	252ºC
Exact Mass	333.15500
PSA	28.54000
LogP	5.28870
Vapour Pressure	7.23E-10mmHg at 25°C
Index of Refraction	1.654

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CL5608700

CHEMICAL NAME :: 8-Azabicyclo(3.2.1)octane, 3-dibenzo(b,e)thiepin-11(6H)-ylidene-8-methyl-

CAS REGISTRY NUMBER :: 27574-24-9

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C22-H23-N-S

MOLECULAR WEIGHT :: 333.52

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 82 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3725415

HS Code	2934999090

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

(1R,5S)-3-[Dibenzo[b,e]thiepin-11(6H)-ylidene]tropane

3-(6H-dibenzo[b,e]thiepin-11-ylidene)-8-methyl-nortropane

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Tropatepine
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
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DC Chemicals Limited
China
Product Name: Tropatepine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Tropatepine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Tropatepine

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.