Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Tropatepine
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Tropatepine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Tropatepine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

27574-24-9

27574-24-9 structure

27574-24-9 structure

Name: Tropatepine
Chemical Name: Tropatepine
CAS Number: 27574-24-9
Molecular Formula: C₂₂H₂₃NS
Molecular Weight: 333.49000
Catalog: Research Areas Neurological Disease
Create Date: 2016-09-01 20:05:47
Modify Date: 2025-08-25 07:51:11
Tropatepine is an anticholinergic muscarinic antagonist and can be used as an antiparkinsonian agent[1]. Tropatepine is used to combat against extrapyramidal syndrome induced by neuroleptic drugs[2].

Name	Tropatepine
Synonyms	(1R,5S)-3-[Dibenzo[b,e]thiepin-11(6H)-ylidene]tropane 3-(6H-dibenzo[b,e]thiepin-11-ylidene)-8-methyl-nortropane

Description	Tropatepine is an anticholinergic muscarinic antagonist and can be used as an antiparkinsonian agent[1]. Tropatepine is used to combat against extrapyramidal syndrome induced by neuroleptic drugs[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. P Celsis, et al. Effect of tropatepine, an anticholinergic drug, on regional cerebral blood flow in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry. 1989 Jul;52(7):917-8. [2]. P Arnoux, et al. Simultaneous determination of tropatepine and its major metabolites by high-performance liquid chromatographic-mass spectrometric identification. Application to metabolic and kinetic studies. J Chromatogr. 1986 Aug 22;381(1):75-82.

Density	1.19g/cm3
Boiling Point	493.1ºC at 760mmHg
Molecular Formula	C₂₂H₂₃NS
Molecular Weight	333.49000
Flash Point	252ºC
Exact Mass	333.15500
PSA	28.54000
LogP	5.28870
Vapour Pressure	7.23E-10mmHg at 25°C
Index of Refraction	1.654

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CL5608700

CHEMICAL NAME :: 8-Azabicyclo(3.2.1)octane, 3-dibenzo(b,e)thiepin-11(6H)-ylidene-8-methyl-

CAS REGISTRY NUMBER :: 27574-24-9

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C22-H23-N-S

MOLECULAR WEIGHT :: 333.52

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 82 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3725415

HS Code	2934999090

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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