521-12-0

521-12-0 structure

Name: Dromostanolone propionate
Chemical Name: dromostanolone propionate
CAS Number: 521-12-0
Molecular Formula: C₂₃H₃₆O₃
Molecular Weight: 360.530
Catalog: Organic raw materials Carboxylic compounds and derivatives Carboxylic esters and their derivatives
Create Date: 2018-05-11 08:00:00
Modify Date: 2025-08-25 10:50:23
Dromostanolone propionate (Drostanolone propionate) is a compound has antitumor activity against breast carcinoma[1]. Dromostanolone propionate inhibits the uptake of oestradiol-17ß by the tumour but has no apparent effect on the uptake by normal breast tissue [2]. Dromostanolone propionate implant pellet produces weight gains in animals and suppresses estrus in female animals[3].

Name	dromostanolone propionate
Synonyms	Androstan-3-one, 2-methyl-17-(1-oxopropoxy)-, (2α,5α,17β)- 2a-Methyl-17b-(1-oxopropoxy)-5a-androstan-3-one Masteril Dromostanolone 17-propionate MDHT (2α,5α,17β)-2-Methyl-3-oxoandrostan-17-yl propionate Dromostanolone propionate Emdisterone 17β-Hydroxy-2α-methyl-5α-androstan-3-one propionate EINECS 208-303-1 5α-Androstan-3-one, 17β-hydroxy-2α-methyl-, propionate Drostanolone propionate Masterone (2α,5α,17β)-2-methyl-3-oxoandrostan-17-yl propanoate Permastril Medrotestron propionate 2a-Methylandrostan-17b-ol-3-one Propionate MFCD01669961 Dromostanolone proprionate Drolban Masterid UNII-X20UZ57G4O 17b-Hydroxy-2a-methyl-5a-androstan-3-one propionate

Description	Dromostanolone propionate (Drostanolone propionate) is a compound has antitumor activity against breast carcinoma[1]. Dromostanolone propionate inhibits the uptake of oestradiol-17ß by the tumour but has no apparent effect on the uptake by normal breast tissue [2]. Dromostanolone propionate implant pellet produces weight gains in animals and suppresses estrus in female animals[3].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Takeuchi S, et al. Clinical experience with dromostanolone propionate (NSC-12198) in breast carcinoma. Saishin Igaku. 1967 May;22(5):1049-54. [2]. N.Deshpande, et al. Accumulation of tritiated oestradiol by human breast tissue. Steroids, 1967 Sep;10(3), 219–232. [3]. Brian H. Vickery . Dromostanolone propionate implant pellet useful for producing weight gains in animals and suppressing estrus in female animals. US3991750A.

Density	1.1±0.1 g/cm3
Boiling Point	445.9±45.0 °C at 760 mmHg
Melting Point	114-120ºC
Molecular Formula	C₂₃H₃₆O₃
Molecular Weight	360.530
Flash Point	190.5±28.8 °C
Exact Mass	360.266449
PSA	43.37000
LogP	5.67
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.522
Storage condition	Controlled Substance, -20?C Freezer

CHEMICAL NAME :: 5-alpha-Androstan-3-one, 17-beta-hydroxy-2-alpha-methyl-, propionate

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,534,1982

Hazard Codes	Xi