Dromostanolone propionate

Modify Date: 2025-08-25 10:50:23

Dromostanolone propionate Structure
Dromostanolone propionate structure
 Common Name Dromostanolone propionate
CAS Number 521-12-0 Molecular Weight 360.530
Density 1.1±0.1 g/cm3 Boiling Point 445.9±45.0 °C at 760 mmHg
Molecular Formula C23H36O3 Melting Point 114-120ºC
MSDS N/A Flash Point 190.5±28.8 °C

 Use of Dromostanolone propionate


Dromostanolone propionate (Drostanolone propionate) is a compound has antitumor activity against breast carcinoma[1]. Dromostanolone propionate inhibits the uptake of oestradiol-17ß by the tumour but has no apparent effect on the uptake by normal breast tissue [2]. Dromostanolone propionate implant pellet produces weight gains in animals and suppresses estrus in female animals[3].

 Names

Name dromostanolone propionate
Synonym More Synonyms

 Dromostanolone propionate Biological Activity

Description Dromostanolone propionate (Drostanolone propionate) is a compound has antitumor activity against breast carcinoma[1]. Dromostanolone propionate inhibits the uptake of oestradiol-17ß by the tumour but has no apparent effect on the uptake by normal breast tissue [2]. Dromostanolone propionate implant pellet produces weight gains in animals and suppresses estrus in female animals[3].
Related Catalog
References

[1]. Takeuchi S, et al. Clinical experience with dromostanolone propionate (NSC-12198) in breast carcinoma. Saishin Igaku. 1967 May;22(5):1049-54.

[2]. N.Deshpande, et al. Accumulation of tritiated oestradiol by human breast tissue. Steroids, 1967 Sep;10(3), 219–232.

[3]. Brian H. Vickery . Dromostanolone propionate implant pellet useful for producing weight gains in animals and suppressing estrus in female animals. US3991750A.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 445.9±45.0 °C at 760 mmHg
Melting Point 114-120ºC
Molecular Formula C23H36O3
Molecular Weight 360.530
Flash Point 190.5±28.8 °C
Exact Mass 360.266449
PSA 43.37000
LogP 5.67
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.522
Storage condition Controlled Substance, -20?C Freezer

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BV8067300
CHEMICAL NAME :
5-alpha-Androstan-3-one, 17-beta-hydroxy-2-alpha-methyl-, propionate
CAS REGISTRY NUMBER :
521-12-0
BEILSTEIN REFERENCE NO. :
3161958
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C23-H36-O3
MOLECULAR WEIGHT :
360.59

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,534,1982

 Safety Information

Hazard Codes Xi

 Synonyms

Androstan-3-one, 2-methyl-17-(1-oxopropoxy)-, (2α,5α,17β)-
2a-Methyl-17b-(1-oxopropoxy)-5a-androstan-3-one
Masteril
Dromostanolone 17-propionate
MDHT
(2α,5α,17β)-2-Methyl-3-oxoandrostan-17-yl propionate
Dromostanolone propionate
Emdisterone
17β-Hydroxy-2α-methyl-5α-androstan-3-one propionate
EINECS 208-303-1
5α-Androstan-3-one, 17β-hydroxy-2α-methyl-, propionate
Drostanolone propionate
Masterone
(2α,5α,17β)-2-methyl-3-oxoandrostan-17-yl propanoate
Permastril
Medrotestron propionate
2a-Methylandrostan-17b-ol-3-one Propionate
MFCD01669961
Dromostanolone proprionate
Drolban
Masterid
UNII-X20UZ57G4O
17b-Hydroxy-2a-methyl-5a-androstan-3-one propionate
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