Dromostanolone propionate

Modify Date: 2024-01-02 13:08:33

Dromostanolone propionate structure	Common Name	Dromostanolone propionate
	CAS Number	521-12-0	Molecular Weight	360.530
	Density	1.1±0.1 g/cm3	Boiling Point	445.9±45.0 °C at 760 mmHg
	Molecular Formula	C₂₃H₃₆O₃	Melting Point	114-120ºC
	MSDS	N/A	Flash Point	190.5±28.8 °C

Use of Dromostanolone propionate

Dromostanolone propionate (Drostanolone propionate) is a compound has antitumor activity against breast carcinoma[1]. Dromostanolone propionate inhibits the uptake of oestradiol-17ß by the tumour but has no apparent effect on the uptake by normal breast tissue [2]. Dromostanolone propionate implant pellet produces weight gains in animals and suppresses estrus in female animals[3].

Name	dromostanolone propionate
Synonym	More Synonyms

Description	Dromostanolone propionate (Drostanolone propionate) is a compound has antitumor activity against breast carcinoma[1]. Dromostanolone propionate inhibits the uptake of oestradiol-17ß by the tumour but has no apparent effect on the uptake by normal breast tissue [2]. Dromostanolone propionate implant pellet produces weight gains in animals and suppresses estrus in female animals[3].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Takeuchi S, et al. Clinical experience with dromostanolone propionate (NSC-12198) in breast carcinoma. Saishin Igaku. 1967 May;22(5):1049-54. [2]. N.Deshpande, et al. Accumulation of tritiated oestradiol by human breast tissue. Steroids, 1967 Sep;10(3), 219–232. [3]. Brian H. Vickery . Dromostanolone propionate implant pellet useful for producing weight gains in animals and suppressing estrus in female animals. US3991750A.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

References

[1]. Takeuchi S, et al. Clinical experience with dromostanolone propionate (NSC-12198) in breast carcinoma. Saishin Igaku. 1967 May;22(5):1049-54.

[2]. N.Deshpande, et al. Accumulation of tritiated oestradiol by human breast tissue. Steroids, 1967 Sep;10(3), 219–232.

[3]. Brian H. Vickery . Dromostanolone propionate implant pellet useful for producing weight gains in animals and suppressing estrus in female animals. US3991750A.

Density	1.1±0.1 g/cm3
Boiling Point	445.9±45.0 °C at 760 mmHg
Melting Point	114-120ºC
Molecular Formula	C₂₃H₃₆O₃
Molecular Weight	360.530
Flash Point	190.5±28.8 °C
Exact Mass	360.266449
PSA	43.37000
LogP	5.67
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.522
Storage condition	Controlled Substance, -20?C Freezer

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BV8067300

CHEMICAL NAME :: 5-alpha-Androstan-3-one, 17-beta-hydroxy-2-alpha-methyl-, propionate

CAS REGISTRY NUMBER :: 521-12-0

BEILSTEIN REFERENCE NO. :: 3161958

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C23-H36-O3

MOLECULAR WEIGHT :: 360.59

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,534,1982

Hazard Codes	Xi

Androstan-3-one, 2-methyl-17-(1-oxopropoxy)-, (2α,5α,17β)-

2a-Methyl-17b-(1-oxopropoxy)-5a-androstan-3-one

Masteril

Dromostanolone 17-propionate

MDHT

(2α,5α,17β)-2-Methyl-3-oxoandrostan-17-yl propionate

Dromostanolone propionate

Emdisterone

17β-Hydroxy-2α-methyl-5α-androstan-3-one propionate

EINECS 208-303-1

5α-Androstan-3-one, 17β-hydroxy-2α-methyl-, propionate

Drostanolone propionate

Masterone

(2α,5α,17β)-2-methyl-3-oxoandrostan-17-yl propanoate

Permastril

Medrotestron propionate

2a-Methylandrostan-17b-ol-3-one Propionate

MFCD01669961

Dromostanolone proprionate

Drolban

Masterid

UNII-X20UZ57G4O

17b-Hydroxy-2a-methyl-5a-androstan-3-one propionate

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Dromostanolone propionate
Price: ￥3788.0/5g ￥1268.0/1g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

Zhejiang Hangyu API Co., Ltd
China
Product Name: Drostanolone Propionate
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Drostanolone Propionate
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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