1270138-40-3

1270138-40-3 structure

Name: NSI-189
Chemical Name: (4-benzylpiperazin-1-yl)-[2-(3-methylbutylamino)pyridin-3-yl]methanone
CAS Number: 1270138-40-3
Molecular Formula: C₂₂H₃₀N₄O
Molecular Weight: 366.500
Catalog: Research Areas Neurological Disease
Create Date: 2016-07-28 21:22:00
Modify Date: 2025-08-20 17:07:32
NSI-189 is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine.IC50 value:Target: in vitro: NSI-189 has been shown to stimulate neurogenesis of human hippocampus-derived neural stem cells in vitro and in vivo. The hippocampus is responsible for the consolidation of information from short-term memory to long-term memory, along with spatial navigation [1] [2].in vivo: NSI-189 has been shown to increase the hippocampal volume of healthy adult mice by 20% [3].

Name	(4-benzylpiperazin-1-yl)-[2-(3-methylbutylamino)pyridin-3-yl]methanone
Synonyms	(4-Benzyl-1-piperazinyl){2-[(3-methylbutyl)amino]-3-pyridinyl}methanone Methanone, [2-[(3-methylbutyl)amino]-3-pyridinyl][4-(phenylmethyl)-1-piperazinyl]- unii-yve9u408zl UNII:YVE9U408ZL NSI-189 NSI189

Description	NSI-189 is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine.IC50 value:Target: in vitro: NSI-189 has been shown to stimulate neurogenesis of human hippocampus-derived neural stem cells in vitro and in vivo. The hippocampus is responsible for the consolidation of information from short-term memory to long-term memory, along with spatial navigation [1] [2].in vivo: NSI-189 has been shown to increase the hippocampal volume of healthy adult mice by 20% [3].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. http://gizmodo.com/5874433/the-pill-that-could-cure-depression-by-growing-your-brain [2]. Compositions to effect neuronal growth US 8030492 B2 [3]. Why Neuralstem Could Provide A 10x Return