Eliglustat hemitartrate is an specific, potent and orally active glucocerebroside synthase inhibitor with an IC50 of 24 nM.
Isophorone, an α,β-unsaturated cyclic ketone, is used as a precursor to polymers[1].
Koumine N-oxide is an alkaloid compound isolated from the herb Gelsemium elegans[1].
GGTI298 is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, strongly inhibiting the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras, with IC50 values of 3 and > 20 μM in vivo, respectively.
Boc-Ala(4-pyridyl)-OH is an alanine derivative[1].
Cantleyoside is a natiural iridoid glycoside that could be found in the Roots of Dipsacus asper[1].
Mitoridine is an indole alkaloid compound isolated from the stem bark of Rauwolfia cumminsii Stapf[1].
Boc-His(Tos)-OH is a histidine derivative[1].
CD38 inhibitor 1 is a potent CD38 inhibitor with IC50s of 7.3 nM and 1.9 nM for human and mouse, respectively[1].
Microcystin-LW is a bacterial metabolite. Microcystin-LW is an analog of microcystin-LR. Microcystin-LW has cellular toxicity[1][2].
Serratenediol (Cathaya D) is a triterpenoid isolated from Pinus banksiana Lamb[1].
DO34 analog is a triazole DAGL(α) inhibitor extracted from patent WO2017096315 A1, compound 100.
Bensulfuron-methyl is a kind of sulfonylurea herbicide widely used to control broad-leaf weeds in rice paddies[1].
2′,7′-Dichlorofluorescein diacetate (DCFH-DA) is a cell-permeable fluorescent probe. 2′,7′-Dichlorofluorescein diacetate can be used to detect the generation of reactive oxygen intermediates and for assessing the overall oxidative stress in toxicological phenomenon[1].
L-Aspartic acid β-hydroxamate is an aspartic acid derivative[1].
Fmoc-Glu(OMe)-OH is a glutamic acid derivative[1].
Phe-Gly hydrate is a Glycine (HY-Y0966) derivative[1].
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-(trifluoromethyl)phenyl)propanoic acid is a phenylalanine derivative[1].
Jolkinolide E is a casbane diterpenoid from the roots of Euphorbia rapulum. Jolkinolide E shows weak selective activity against HepG2, MCF-7, and C6 cell lines[1].
Furegrelate Sodium (U-63557A) is a potent, orally available, and selective thromboxane synthase inhibitor. Furegrelate Sodium inhibits human platelet microsomal thromboxane A2 (TxA2) synthase with an IC50 of 15 nM. Furegrelate Sodium is being developed as an antiplatelet agent[1][2].
Methyl pentadecanoate-d29 is the deuterium labeled Methyl pentadecanoate[1].
Bacopaside N2 is a diglycosidic saponin[1].
5-Hydroxy-3,7-dimethoxyflavone (compound 1) can be isolated from Kaempferia parviflora, but has no significant toxicity to malaria parasites, fungi, and bacteria[1].
N,N′-Dibenzoyl-L-cystine is a cysteine derivative[1].
N1,N1,N3,N3-Tetramethylpropane-1,3-diamine-d18 is the deuterium labeled N1,N1,N3,N3-Tetramethylpropane-1,3-diamine[1].
(-)-Fenchone, a bicyclic monoterpene, is widely distributed in plants and found in essential oils from Thuja occidentalis. (-)-Fenchone is oxidized to 6-endo-hydroxyfenchone, 6-exo-hydroxyfenchone and 10-hydroxyfenchone derivatives by CYP2A6 and CYP2B6 in human liver microsomes with CYP2A6 playing a more important role than CYP2B6[1].
trans-N-Methyl-4-methoxyproline is a natural product that can be isolated from the stems of Petiveria alliacea and is also a Proline derivative[1].
N-Methyl lactam (Compound 3b), a peramiue analogue, has feeding-deterrent activity against adult weevils[1].
6-[(1R,2S)-2,3-dihydroxy-1-methoxy-3-methylbutyl]-7-methoxy- can be isolated from Angelica dahurica stem, for the first time from a plant source[1].