153049-49-1

153049-49-1 structure

Name: PD 145065
Chemical Name: pd-145065
CAS Number: 153049-49-1
Molecular Formula: C₅₂H₆₇N₇O₁₀
Molecular Weight: 950.12900
Catalog: Research Areas Others
Create Date: 2018-12-28 19:45:56
Modify Date: 2025-08-21 15:54:39
PD 145065 is a highly potent but non-selective endothelin receptor antagonist with an IC50 value of 4 nM for the ETA receptor for rabbit renal artery vascular smooth muscle cells[1].

Name	pd-145065

Description	PD 145065 is a highly potent but non-selective endothelin receptor antagonist with an IC50 value of 4 nM for the ETA receptor for rabbit renal artery vascular smooth muscle cells[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Warner TD, et al. Reversal of established responses to endothelin-1 in vivo and in vitro by the endothelin receptor antagonists, BQ-123 and PD 145065. Br J Pharmacol. 1994 May;112(1):207-13.