PD 145065

Modify Date: 2025-08-21 15:54:39

PD 145065 Structure
PD 145065 structure
 Common Name PD 145065
CAS Number 153049-49-1 Molecular Weight 950.12900
Density 1.24g/cm3 Boiling Point 1252.1ºC at 760mmHg
Molecular Formula C52H67N7O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PD 145065


PD 145065 is a highly potent but non-selective endothelin receptor antagonist with an IC50 value of 4 nM for the ETA receptor for rabbit renal artery vascular smooth muscle cells[1].

 Names

Name pd-145065

 PD 145065 Biological Activity

Description PD 145065 is a highly potent but non-selective endothelin receptor antagonist with an IC50 value of 4 nM for the ETA receptor for rabbit renal artery vascular smooth muscle cells[1].
Related Catalog
References

[1]. Warner TD, et al. Reversal of established responses to endothelin-1 in vivo and in vitro by the endothelin receptor antagonists, BQ-123 and PD 145065. Br J Pharmacol. 1994 May;112(1):207-13.  

 Chemical & Physical Properties

Density 1.24g/cm3
Boiling Point 1252.1ºC at 760mmHg
Molecular Formula C52H67N7O10
Molecular Weight 950.12900
Exact Mass 949.49500
PSA 264.99000
LogP 6.61280
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.59
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Chemsrc provides PD 145065(CAS#:153049-49-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of PD 145065 are included as well.>> amp version: PD 145065

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