PD 166793
Modify Date: 2025-08-23 10:00:21
PD 166793 structure
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Common Name | PD 166793 | ||
|---|---|---|---|---|
| CAS Number | 199850-67-4 | Molecular Weight | 412.29800 | |
| Density | 1.457g/cm3 | Boiling Point | 562.069ºC at 760 mmHg | |
| Molecular Formula | C17H18BrNO4S | Melting Point | 192-193℃ | |
| MSDS | N/A | Flash Point | 293.729ºC | |
Use of PD 166793PD-166793 is a cell-permeable biphenylsulfonylvaline compound that acts as a potent inhibitor against MMP-2, -3, and -13 (IC50 = 47, 12, and 8 nM, respectively) and a weaker inhibitor against AMP deaminase (20% inhibition at 0.1 μM), MMP-1, -7, -9, and -14 (IC50 = 6.1, 7.2, 7.9, and 0.24 μM, respectively). Shown to offer therapeutic benefits in vivo in various animal models of heart failure and diabetes. |
| Name | (2S)-2-[[4-(4-bromophenyl)phenyl]sulfonylamino]-3-methylbutanoic acid |
|---|
| Density | 1.457g/cm3 |
|---|---|
| Boiling Point | 562.069ºC at 760 mmHg |
| Melting Point | 192-193℃ |
| Molecular Formula | C17H18BrNO4S |
| Molecular Weight | 412.29800 |
| Flash Point | 293.729ºC |
| Exact Mass | 411.01400 |
| PSA | 91.85000 |
| LogP | 4.97530 |
| Vapour Pressure | 0mmHg at 25°C |
| Index of Refraction | 1.597 |
| Storage condition | Desiccate at +4°C |
| Precursor 3 | |
|---|---|
| DownStream 0 | |