PD-1/PD-L1-IN-23

Modify Date: 2024-01-11 22:21:45

PD-1/PD-L1-IN-23 Structure
PD-1/PD-L1-IN-23 structure
Common Name PD-1/PD-L1-IN-23
CAS Number 2597056-04-5 Molecular Weight 703.41
Density N/A Boiling Point N/A
Molecular Formula C32H30BrCl2N3O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PD-1/PD-L1-IN-23


PD-1/PD-L1-IN-23 is a potent and orally active inhibitor of PD-1/PD-L1. PD-1/PD-L1-IN-23 is an ester prodrug of L7. L7 is a benzo[c][1,2,5]oxadiazole derivative and biologically evaluated as inhibitors of PD-L1. PD-1/PD-L1-IN-23 displays significant antitumor effects in tumor models of syngeneic and PD-L1 humanized mice[1].

 Names

Name PD-1/PD-L1-IN-23

 PD-1/PD-L1-IN-23 Biological Activity

Description PD-1/PD-L1-IN-23 is a potent and orally active inhibitor of PD-1/PD-L1. PD-1/PD-L1-IN-23 is an ester prodrug of L7. L7 is a benzo[c][1,2,5]oxadiazole derivative and biologically evaluated as inhibitors of PD-L1. PD-1/PD-L1-IN-23 displays significant antitumor effects in tumor models of syngeneic and PD-L1 humanized mice[1].
Related Catalog
Target

PD-1/PD-L1[1]

References

[1]. Liu L, et al. Syntheses, Biological Evaluations, and Mechanistic Studies of Benzo[c][1,2,5]oxadiazole Derivatives as Potent PD-L1 Inhibitors with In Vivo Antitumor Activity. J Med Chem. 2021;64(12):8391-8409.

 Chemical & Physical Properties

Molecular Formula C32H30BrCl2N3O6
Molecular Weight 703.41